PlainPill

Choline vs DHA for memory

Short answer: For memory, more users report improvement with Choline — 90% of 31 reports, versus 80% of 20 for DHA.

Choline has 280 meta-analyses and 460 randomized trials on PubMed; DHA has 365 and 1,607.

Based on 608 reports about Choline and 133 about DHA. Not medical advice.

Choline
Supplement
DHA
Supplement
Users say it helped46%helped170 reports · high confidence76%helped39 reports · medium confidence
Verdict
Mixed
Mostly positive
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs280 / 460365 / 1,607
Mainly used for
Focus
% reporting improvement
88% (56)89% (9)
Mood
% reporting improvement
22% (51)100% (11)
Memory
% reporting improvement
90% (31)80% (20)
Anxiety
% reporting improvement
63% (19)100% (2)
Energy
% reporting improvement
47% (15)100% (3)
Common side effectsdepression, headache, fatigue, anxietyNone reported
Typical dose reported200-500 mg / on days diet lacks choline1.5 g / daily
Choline
Latest review conclusion

This guideline should enable addressing suboptimal and deficient status of a bundle of MNs in at-risk diseases. In particular, it offers practical advice on MN provision and monitoring during nutritional support.

Clin Nutr, 2022 ↗
What a user said
“I take choline with it and I feel it for couple of hours..although mild.”
Full Choline profile →
DHA
Latest review conclusion

In summary, there is evidence that n-3 PUFAs supplementation monotherapy improves clinical symptoms and cognitive performances in children and adolescents with ADHD, and that these youth have a deficiency in n-3 PUFAs levels. Our findings provide further support to the rationale for using n-3 PUFAs as a treatment option for ADHD.

Neuropsychopharmacology, 2018 ↗
What a user said
“I have been on the mr.happy stack for about two months(uridine+DHA+choline) and it works wonders for me.”
Full DHA profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate