PlainPill

Curcumin vs Kanna for mood

Short answer: For mood, users rate them about the same: 96% report improvement with Curcumin (45 reports) and 94% with Kanna (84 reports).

Curcumin has 538 meta-analyses and 553 randomized trials on PubMed; Kanna has 8 and 0.

Based on 544 reports about Curcumin and 231 about Kanna. Not medical advice.

Curcumin
Supplement
Kanna
Supplement
Users say it helped61%helped180 reports · high confidence77%helped102 reports · high confidence
Verdict
Mostly positive
Mostly positive
ResearchAResearch: StrongBResearch: Moderate
Meta-analyses / RCTs538 / 5538 / 0
Mainly used for
Mood
% reporting improvement
96% (45)94% (84)
Pain & inflammation
% reporting improvement
91% (104)—
Anxiety
% reporting improvement
93% (15)88% (42)
Energy
% reporting improvement
83% (6)92% (13)
Focus
% reporting improvement
78% (9)100% (6)
Common side effectsvivid dreams, headache, nausea, dht suppressiondrowsiness, appetite suppression, brain fog, agitation
Typical dose reported1000 mg / daily300mg sublingual
Curcumin
Latest review conclusion

Curcumin and Curcuma longa Extract may improve symptoms and inflammation levels in people with arthritis. However, due to the low quality and small quantity of RCTs, the conclusions need to be interpreted carefully.

Front Immunol, 2022 ↗
What a user said
“I recently stopped taking Curcumin because of its affect on DHT and I was looking for an alternative measure to deal with inflammation as I feel it really helped with anxiety/depression.”
Full Curcumin profile →
Kanna
Latest review conclusion

Additional top genes influence stress, immune, fear and threat-related processes, previously hypothesized to underlie PTSD neurobiology. These findings strengthen our understanding of neurobiological systems relevant to PTSD pathophysiology, while also opening new areas for investigation.

Nat Genet, 2024 ↗
What a user said
“Kanna tablets. Dissolve under the tongue...I can't sing Kannas praises enough. It's the instant cure for my brain fog, lack of energy, and lack of motivation.”
Full Kanna profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate