Curcumin vs TB-500 for pain & inflammation
Short answer: For pain & inflammation, users rate them about the same: 88% report improvement with Curcumin (78 reports) and 84% with TB-500 (168 reports).
Curcumin has 538 meta-analyses and 553 randomized trials on PubMed; TB-500 has 0 and 3.
Based on 402 reports about Curcumin and 652 about TB-500. Not medical advice.
| Curcumin Supplement | TB-500 Peptide | |
|---|---|---|
| User score | 48 | 49 |
| Verdict | Mixed | Mostly positive |
| Positive of reports that state an outcome | 57% | 67% |
| Reports | 402 | 652 |
| Research | AResearch: Strong | CResearch: Limited |
| Meta-analyses / RCTs | 538 / 553 | 0 / 3 |
| Mainly used for | ||
| Weight loss % reporting improvement | — | 100% (8) |
| Appetite % reporting improvement | — | 100% (2) |
| Focus % reporting improvement | 71% (7) | 50% (2) |
| Energy % reporting improvement | 75% (4) | 50% (4) |
| Sleep % reporting improvement | 75% (4) | 60% (5) |
| Anxiety % reporting improvement | 92% (12) | 29% (7) |
| Mood % reporting improvement | 94% (33) | 89% (9) |
| Memory % reporting improvement | 100% (8) | — |
| Performance % reporting improvement | 33% (3) | 100% (17) |
| Recovery % reporting improvement | 89% (9) | 97% (208) |
| Pain & inflammation % reporting improvement | 88% (78) | 84% (168) |
| Digestion % reporting improvement | — | 100% (2) |
| Libido % reporting improvement | 20% (5) | — |
| Hormones % reporting improvement | 33% (3) | — |
| Heart & lipids % reporting improvement | 100% (2) | 60% (5) |
| Skin & hair % reporting improvement | 80% (5) | 84% (19) |
| Immunity % reporting improvement | 100% (3) | 60% (5) |
| Longevity % reporting improvement | 100% (2) | — |
| Common side effects | stomach issues, vivid dreams, headache, nausea | anxiety, fatigue, dizziness, allergic reaction |
| Typical dose reported | 1000 mg / daily | Not listed |
CurcuminFull Curcumin profile →
Latest review conclusion
Curcumin and Curcuma longa Extract may improve symptoms and inflammation levels in people with arthritis. However, due to the low quality and small quantity of RCTs, the conclusions need to be interpreted carefully.
Front Immunol, 2022 ↗What a user said
“I recently stopped taking Curcumin because of its affect on DHT and I was looking for an alternative measure to deal with inflammation as I feel it really helped with anxiety/depression.”
TB-500Full TB-500 profile →
What a user said
“They reduce neuroinflammation in the brain caused by either head injuries or drug abuse. Ive used them both for this and it works.”
Related comparisons
Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate