PlainPill

Curcumin vs Kratom for pain & inflammation

Short answer: For pain & inflammation, more users report improvement with Kratom — 93% of 28 reports, versus 88% of 78 for Curcumin.

Curcumin has 538 meta-analyses and 553 randomized trials on PubMed; Kratom has 18 and 5.

Based on 402 reports about Curcumin and 421 about Kratom. Not medical advice.

Curcumin
Supplement
Kratom
Substance
User score4850
Verdict
Mixed
Mixed
Positive
of reports that state an outcome
57%42%
Reports402421
ResearchAResearch: StrongBResearch: Moderate
Meta-analyses / RCTs538 / 55318 / 5
Mainly used for
Weight loss
% reporting improvement
—50% (2)
Appetite
% reporting improvement
—100% (3)
Focus
% reporting improvement
71% (7)77% (31)
Energy
% reporting improvement
75% (4)78% (54)
Sleep
% reporting improvement
75% (4)71% (7)
Anxiety
% reporting improvement
92% (12)86% (69)
Mood
% reporting improvement
94% (33)85% (97)
Memory
% reporting improvement
100% (8)0% (5)
Performance
% reporting improvement
33% (3)100% (3)
Recovery
% reporting improvement
89% (9)—
Pain & inflammation
% reporting improvement
88% (78)93% (28)
Digestion
% reporting improvement
—33% (9)
Libido
% reporting improvement
20% (5)0% (12)
Hormones
% reporting improvement
33% (3)22% (9)
Heart & lipids
% reporting improvement
100% (2)—
Skin & hair
% reporting improvement
80% (5)—
Immunity
% reporting improvement
100% (3)—
Longevity
% reporting improvement
100% (2)—
Common side effectsstomach issues, vivid dreams, headache, nauseawithdrawal, dependence, addiction, tolerance
Typical dose reported1000 mg / daily4 g / 2x daily
Curcumin
Latest review conclusion

Curcumin and Curcuma longa Extract may improve symptoms and inflammation levels in people with arthritis. However, due to the low quality and small quantity of RCTs, the conclusions need to be interpreted carefully.

Front Immunol, 2022 ↗
What a user said
“I recently stopped taking Curcumin because of its affect on DHT and I was looking for an alternative measure to deal with inflammation as I feel it really helped with anxiety/depression.”
Full Curcumin profile →
Kratom
Latest review conclusion

Based on our analysis, patients using <20 g of kratom/d could be initiated on opioid agonist therapy with 4/1 mg-8/2 mg buprenorphine-naloxone/d, while patients using kratom doses >40 g/d could be initiated with 12/3 mg-16/4 mg of buprenorphine-naloxone/day.

J Addict Med, 2021 ↗
What a user said
“Green or white Kratom powder. My productivity and overall mood have skyrocketed. I dose 4 grams once per day and it’s worked wonders.”
Full Kratom profile →

Related comparisons

Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate