PlainPill

Curcumin vs GHK-Cu for pain & inflammation

Short answer: For pain & inflammation, users rate them about the same: 88% report improvement with Curcumin (78 reports) and 89% with GHK-Cu (28 reports).

Curcumin has 538 meta-analyses and 553 randomized trials on PubMed; GHK-Cu has 0 and 1.

Based on 402 reports about Curcumin and 457 about GHK-Cu. Not medical advice.

Curcumin
Supplement
GHK-Cu
Peptide
User score4854
Verdict
Mixed
Mostly positive
Positive
of reports that state an outcome
57%62%
Reports402457
ResearchAResearch: StrongCResearch: Limited
Meta-analyses / RCTs538 / 5530 / 1
Mainly used for
Weight loss
% reporting improvement
—88% (8)
Focus
% reporting improvement
71% (7)75% (4)
Energy
% reporting improvement
75% (4)—
Sleep
% reporting improvement
75% (4)80% (5)
Anxiety
% reporting improvement
92% (12)50% (4)
Mood
% reporting improvement
94% (33)86% (7)
Memory
% reporting improvement
100% (8)—
Performance
% reporting improvement
33% (3)100% (5)
Recovery
% reporting improvement
89% (9)95% (21)
Pain & inflammation
% reporting improvement
88% (78)89% (28)
Digestion
% reporting improvement
—100% (4)
Libido
% reporting improvement
20% (5)—
Hormones
% reporting improvement
33% (3)—
Heart & lipids
% reporting improvement
100% (2)33% (3)
Skin & hair
% reporting improvement
80% (5)87% (193)
Immunity
% reporting improvement
100% (3)100% (4)
Longevity
% reporting improvement
100% (2)100% (2)
Common side effectsstomach issues, vivid dreams, headache, nauseainjection site, redness, stinging, injection pain
Typical dose reported1000 mg / dailyNot listed
Curcumin
Latest review conclusion

Curcumin and Curcuma longa Extract may improve symptoms and inflammation levels in people with arthritis. However, due to the low quality and small quantity of RCTs, the conclusions need to be interpreted carefully.

Front Immunol, 2022 ↗
What a user said
“I recently stopped taking Curcumin because of its affect on DHT and I was looking for an alternative measure to deal with inflammation as I feel it really helped with anxiety/depression.”
Full Curcumin profile →
GHK-Cu
What a user said
“Love it. 44 F. Totally helped even out my skin tone (Irish red cheeks), reduced wrinkles on my forehead and neck, thickened my hair which had been thinning, and grew my eye lashes.”
Full GHK-Cu profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate