PlainPill

Clomiphene vs Zinc for hormones

Short answer: For hormones, more users report improvement with Clomiphene — 95% of 64 reports, versus 88% of 94 for Zinc.

Clomiphene has 218 meta-analyses and 531 randomized trials on PubMed; Zinc has 220 and 555.

Based on 224 reports about Clomiphene and 1,594 about Zinc. Not medical advice.

Clomiphene
Medication
Zinc
Supplement
Users say it helped53%helped76 reports · medium confidence59%helped510 reports · high confidence
Verdict
Mixed
Mixed
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs218 / 531220 / 555
Mainly used for
Hormones
% reporting improvement
95% (64)88% (94)
Libido
% reporting improvement
50% (10)90% (120)
Mood
% reporting improvement
22% (23)81% (68)
Sleep
% reporting improvement
—84% (76)
Energy
% reporting improvement
67% (6)74% (57)
Common side effectsmood swings, emotional, fatigue, vision sidesnausea, stomach issues, vomiting, copper deficiency
Typical dose reportedNot listed75 mg
Clomiphene
Latest review conclusion

Clomiphene citrate increased sperm concentration and motility and could be considered as a safe therapy for improving sperm parameters in infertile males.

Andrology, 2023 ↗
What a user said
“At 35 years old, I literally feel as good as I did in high school again in every aspect: motivation, libido, energy, wellbeing, etc.”
Full Clomiphene profile →
Zinc
Latest review conclusion

Acne patients have decreased serum zinc levels. Zinc is effective for the treatment of acne, particularly at decreasing the number of inflammatory papules, when used as monotherapy or as an adjunctive treatment.

Dermatol Ther, 2020 ↗
What a user said
“I had actual energy in the mornings for the first time I could remember.”
Full Zinc profile →

Related comparisons

Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate