Clomiphene vs Tamoxifen for hormones
Short answer: For hormones, users rate them about the same: 95% report improvement with Clomiphene (64 reports) and 98% with Tamoxifen (49 reports).
Clomiphene has 218 meta-analyses and 531 randomized trials on PubMed; Tamoxifen has 479 and 1,597.
Based on 224 reports about Clomiphene and 298 about Tamoxifen. Not medical advice.
| Clomiphene Medication | Tamoxifen Medication | |
|---|---|---|
| Users say it helped | 53%helped76 reports · medium confidence | 64%helped75 reports · medium confidence |
| Verdict | Mixed | Mostly positive |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 218 / 531 | 479 / 1,597 |
| Mainly used for | ||
| Hormones % reporting improvement | 95% (64) | 98% (49) |
| Mood % reporting improvement | 22% (23) | 0% (2) |
| Libido % reporting improvement | 50% (10) | 57% (7) |
| Energy % reporting improvement | 67% (6) | 100% (5) |
| Performance % reporting improvement | 80% (5) | 50% (2) |
| Common side effects | mood swings, emotional, fatigue, vision sides | fatigue, depression, low libido, headache |
| Typical dose reported | Not listed | Not listed |
Clomiphene citrate increased sperm concentration and motility and could be considered as a safe therapy for improving sperm parameters in infertile males.
Andrology, 2023 ↗“At 35 years old, I literally feel as good as I did in high school again in every aspect: motivation, libido, energy, wellbeing, etc.”
5 years of adjuvant tamoxifen safely reduces 15-year risks of breast cancer recurrence and death. ER status was the only recorded factor importantly predictive of the proportional reductions. Hence, the absolute risk reductions produced by tamoxifen depend on the absolute breast cancer risks (after any chemotherapy) without tamoxifen.
Lancet, 2011 ↗“This is now 2nd day on nolva and I swaer my balls are about back to normal. Energy is a bit better”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate