PlainPill

Clomiphene vs Vitamin D for hormones

Short answer: For hormones, users rate them about the same: 95% report improvement with Clomiphene (64 reports) and 91% with Vitamin D (75 reports).

Clomiphene has 218 meta-analyses and 531 randomized trials on PubMed; Vitamin D has 3,251 and 4,560.

Based on 224 reports about Clomiphene and 3,058 about Vitamin D. Not medical advice.

Clomiphene
Medication
Vitamin D
Supplement
Users say it helped53%helped76 reports · medium confidence67%helped1,101 reports · high confidence
Verdict
Mixed
Mostly positive
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs218 / 5313,251 / 4,560
Mainly used for
Mood
% reporting improvement
22% (23)88% (393)
Energy
% reporting improvement
67% (6)87% (255)
Hormones
% reporting improvement
95% (64)91% (75)
Sleep
% reporting improvement
—52% (119)
Immunity
% reporting improvement
—98% (94)
Common side effectsmood swings, emotional, fatigue, vision sidesinsomnia, anxiety, hypercalcemia, nausea
Typical dose reportedNot listed10,000-20,000 IU / daily
Clomiphene
Latest review conclusion

Clomiphene citrate increased sperm concentration and motility and could be considered as a safe therapy for improving sperm parameters in infertile males.

Andrology, 2023 ↗
What a user said
“At 35 years old, I literally feel as good as I did in high school again in every aspect: motivation, libido, energy, wellbeing, etc.”
Full Clomiphene profile →
Vitamin D
Latest review conclusion

These results indicate that the prevalence of vitamin D deficiency was more elevated in obese subjects. The vitamin D deficiency was associated with obesity irrespective of age, latitude, cut-offs to define vitamin D deficiency and the Human Development Index of the study location.

Obes Rev, 2015 ↗
What a user said
“First thing I noticed was my mood & libido, I have more 'feeling/sensitivity' down there.”
Full Vitamin D profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate