Citrulline vs Magnesium for heart & lipids
Short answer: For heart & lipids, users rate them about the same: 100% report improvement with Citrulline (14 reports) and 96% with Magnesium (26 reports).
Citrulline has 51 meta-analyses and 258 randomized trials on PubMed; Magnesium has 82 and 210.
Based on 157 reports about Citrulline and 2,391 about Magnesium. Not medical advice.
| Citrulline Supplement | Magnesium Supplement | |
|---|---|---|
| Users say it helped | 84%helped58 reports · medium confidence | 73%helped956 reports · high confidence |
| Verdict | Mostly positive | Mostly positive |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 51 / 258 | 82 / 210 |
| Mainly used for | ||
| Sleep % reporting improvement | — | 88% (430) |
| Anxiety % reporting improvement | — | 90% (289) |
| Mood % reporting improvement | — | 82% (118) |
| Energy % reporting improvement | 75% (4) | 75% (83) |
| Performance % reporting improvement | 100% (31) | 88% (17) |
| Common side effects | erectile dysfunction, tooth erosion, tooth enamel, gerd | diarrhea, drowsiness, stomach issues, vivid dreams |
| Typical dose reported | 1 g | 500 mg / daily |
Supplementation of some but not all micronutrients may benefit cardiometabolic health. This study highlights the importance of micronutrient diversity and the balance of benefits and risks to promote and maintain cardiovascular health in diverse populations. (Antioxidant Supplementation in the Prevention and Treatment of Cardiovascular Diseases; CRD42022315165).
J Am Coll Cardiol, 2022 ↗“try all the standard vasodilators - citrulline and agmatine helped me a lot.”
This review confirms that the quality of literature is substandard for physicians to make well-informed recommendations on usage of oral magnesium for older adults with insomnia. However, given that oral magnesium is very cheap and widely available, RCT evidence may support oral magnesium supplements (less than 1 g quantities given up to three times a day) for insomnia symptoms.
BMC Complement Med Ther, 2021 ↗“after supplementing with 400mg of Magnesium daily. Winter blues hit me hard and my multivitamin wasn't doing any justice, but once I began supplementing Magnesium, everything changed.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate