PlainPill

Citrulline vs Whey Protein for performance

Short answer: For performance, users rate them about the same: 100% report improvement with Citrulline (31 reports) and 100% with Whey Protein (51 reports).

Citrulline has 51 meta-analyses and 258 randomized trials on PubMed; Whey Protein has 97 and 691.

Based on 157 reports about Citrulline and 305 about Whey Protein. Not medical advice.

Citrulline
Supplement
Whey Protein
Supplement
Users say it helped84%helped58 reports · medium confidence83%helped128 reports · high confidence
Verdict
Mostly positive
Mostly positive
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs51 / 25897 / 691
Mainly used for
Performance
% reporting improvement
100% (31)100% (51)
Recovery
% reporting improvement
100% (2)100% (31)
Libido
% reporting improvement
90% (20)—
Heart & lipids
% reporting improvement
100% (14)—
Digestion
% reporting improvement
—0% (8)
Common side effectserectile dysfunction, tooth erosion, tooth enamel, gerdstomach issues, acne, constipation, throat tightness
Typical dose reported1 g30 g / 2x daily
Citrulline
Latest review conclusion

Supplementation of some but not all micronutrients may benefit cardiometabolic health. This study highlights the importance of micronutrient diversity and the balance of benefits and risks to promote and maintain cardiovascular health in diverse populations. (Antioxidant Supplementation in the Prevention and Treatment of Cardiovascular Diseases; CRD42022315165).

J Am Coll Cardiol, 2022 ↗
What a user said
“try all the standard vasodilators - citrulline and agmatine helped me a lot.”
Full Citrulline profile →
Whey Protein
Latest review conclusion

Analysis revealed that chronic and without professional guidance use of whey protein supplementation may cause some adverse effects specially on kidney and liver function. Presented data support a need for future studies co-relating the use of different types of whey protein with and without exercise to better see the impact on human physical health.

Appl Physiol Nutr Metab, 2021 ↗
What a user said
“Coffee with cream, has to be a cream or fake creamer with a whey protein, doesn't. It gives me a gentle but potent energy boost with no headache and no jitters.”
Full Whey Protein profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate