Bromantane vs SAM-E for mood
Short answer: For mood, users rate them about the same: 95% report improvement with Bromantane (74 reports) and 92% with SAM-E (114 reports).
Bromantane has 1 meta-analyses and 0 randomized trials on PubMed; SAM-E has 3 and 1.
Based on 518 reports about Bromantane and 284 about SAM-E. Not medical advice.
| Bromantane Supplement | SAM-E Supplement | |
|---|---|---|
| Users say it helped | 69%helped186 reports · high confidence | 63%helped131 reports · high confidence |
| Verdict | Mostly positive | Mostly positive |
| Research | BResearch: Moderate | BResearch: Moderate |
| Meta-analyses / RCTs | 1 / 0 | 3 / 1 |
| Mainly used for | ||
| Mood % reporting improvement | 95% (74) | 92% (114) |
| Energy % reporting improvement | 96% (90) | 87% (23) |
| Focus % reporting improvement | 89% (70) | 100% (13) |
| Anxiety % reporting improvement | 96% (46) | 67% (21) |
| Performance % reporting improvement | 89% (9) | — |
| Common side effects | jitteriness, insomnia, headache, irritability | insomnia, jitteriness, stomach issues, anxiety |
| Typical dose reported | 130 mg / daily | 200-400 mg / daily |
The data from the meta-analysis showed that plant adaptogens could provide a number of benefits in the treatment of chronic fatigue, cognitive impairment, and immune protection. In the future, there is great potential to register medicinal products that contain plant adaptogens for therapeutic purposes.
Nutrients, 2021 ↗“Bromantane will reset dopamine baseline and stim tolerance but it also gives me crazy energy like a kid again.”
Our results showed that robotic surgery contributed positively to some perioperative outcomes but longer operative times remained a shortcoming. Better quality evidence is needed to guide surgical decision making regarding the precise clinical targets of this innovation in the next generation of its use.
Surg Endosc, 2016 ↗“I also take SAM-e in the morning (200mg or 400mg per day depending on how I'm feeling) for my general depression/anxiety.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate