PlainPill

Apple Cider Vinegar vs MOTS-C for blood sugar

Short answer: For blood sugar, more users report improvement with Apple Cider Vinegar — 100% of 5 reports, versus 40% of 5 for MOTS-C.

Apple Cider Vinegar has 6 meta-analyses and 5 randomized trials on PubMed; MOTS-C has 0 and 4.

Based on 51 reports about Apple Cider Vinegar and 203 about MOTS-C. Not medical advice.

Apple Cider Vinegar
Supplement
MOTS-C
Peptide
User score5550
Verdict
Mostly positive
Mixed
Positive
of reports that state an outcome
84%49%
Reports51203
ResearchBResearch: ModerateCResearch: Limited
Meta-analyses / RCTs6 / 50 / 4
Mainly used for
Weight loss
% reporting improvement
—85% (13)
Appetite
% reporting improvement
100% (2)—
Focus
% reporting improvement
100% (2)83% (6)
Energy
% reporting improvement
75% (4)84% (74)
Sleep
% reporting improvement
100% (2)0% (5)
Mood
% reporting improvement
—100% (5)
Performance
% reporting improvement
—85% (34)
Digestion
% reporting improvement
83% (6)—
Blood sugar
% reporting improvement
100% (5)40% (5)
Immunity
% reporting improvement
—50% (2)
Common side effectsstomach issuesfatigue, insomnia, injection site, dizziness
Typical dose reported2 tbspNot listed
Apple Cider Vinegar
Latest review conclusion

We found a significant favorable effect of ACV consumption on FPG and blood lipid levels.

BMC Complement Med Ther, 2021 ↗
What a user said
“Apple Cider Vinegar and water. It's changed my gut health for the better.”
Full Apple Cider Vinegar profile →
MOTS-C
What a user said
“Taking these makes me feel wildly energetic all day—zero afternoon slumps, and my endurance during cardio feels bottomless.”
Full MOTS-C profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate