Apple Cider Vinegar vs Berberine for blood sugar
Short answer: For blood sugar, more users report improvement with Apple Cider Vinegar — 100% of 5 reports, versus 86% of 58 for Berberine.
Apple Cider Vinegar has 6 meta-analyses and 5 randomized trials on PubMed; Berberine has 109 and 110.
Based on 51 reports about Apple Cider Vinegar and 294 about Berberine. Not medical advice.
| Apple Cider Vinegar Supplement | Berberine Supplement | |
|---|---|---|
| User score | 55 | 47 |
| Verdict | Mostly positive | Mixed |
| Positive of reports that state an outcome | 84% | 56% |
| Reports | 51 | 294 |
| Research | BResearch: Moderate | AResearch: Strong |
| Meta-analyses / RCTs | 6 / 5 | 109 / 110 |
| Mainly used for | ||
| Weight loss % reporting improvement | — | 84% (19) |
| Appetite % reporting improvement | 100% (2) | 87% (15) |
| Focus % reporting improvement | 100% (2) | 33% (6) |
| Energy % reporting improvement | 75% (4) | 90% (21) |
| Sleep % reporting improvement | 100% (2) | 75% (4) |
| Anxiety % reporting improvement | — | 50% (8) |
| Mood % reporting improvement | — | 86% (14) |
| Performance % reporting improvement | — | 67% (3) |
| Pain & inflammation % reporting improvement | — | 100% (4) |
| Digestion % reporting improvement | 83% (6) | 60% (15) |
| Hormones % reporting improvement | — | 67% (3) |
| Blood sugar % reporting improvement | 100% (5) | 86% (58) |
| Heart & lipids % reporting improvement | — | 92% (13) |
| Longevity % reporting improvement | — | 50% (2) |
| Common side effects | stomach issues | stomach issues, fatigue, constipation, anxiety |
| Typical dose reported | 2 tbsp | 400-500 mg / daily |
We found a significant favorable effect of ACV consumption on FPG and blood lipid levels.
BMC Complement Med Ther, 2021 ↗“Apple Cider Vinegar and water. It's changed my gut health for the better.”
Treatment with berberine may be safe since it does not increase the incidence of total adverse events and the risk of hypoglycemia. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=292975, identifier CRD42021292975.
Front Pharmacol, 2022 ↗“I started berberine and inositol, and began having energy that I did not have before. Somehow, my recovery after working out wasn't as long either.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate