PlainPill

ALA vs Berberine Phytosome for blood sugar

Short answer: For blood sugar, users rate them about the same: 100% report improvement with ALA (9 reports) and 100% with Berberine Phytosome (8 reports).

ALA has 100 meta-analyses and 243 randomized trials on PubMed; Berberine Phytosome has 0 and 0.

Based on 320 reports about ALA and 32 about Berberine Phytosome. Not medical advice.

ALA
Supplement
Berberine Phytosome
Supplement
Users say it helped65%helped54 reports · medium confidence86%helped14 reports · few reports
Verdict
Mostly positive
Mostly positive
ResearchAResearch: StrongDResearch: None
Meta-analyses / RCTs100 / 2430 / 0
Mainly used for
Energy
% reporting improvement
100% (15)50% (4)
Blood sugar
% reporting improvement
100% (9)100% (8)
Focus
% reporting improvement
80% (5)100% (2)
Pain & inflammation
% reporting improvement
86% (7)—
Common side effectsliver damage, headache, fatty liver, mercury brainfatigue, drowsiness, depression, diarrhea
Typical dose reported600 mg / daily550 mg / 2x daily
ALA
Latest review conclusion

ALA treatment had favorable effects on DSPN by reducing sensory symptoms, and it resulted in a dose-dependent response relative to the placebo for TSS and the global satisfaction score. The use of ALA to prevent neurological symptoms should be further researched.

Nutrients, 2023 ↗
What a user said
“I also take alcar, alpha lipoic acid, choline, and pqq, but... there is some difference with these, but not as major as with CoQ10.”
Full ALA profile →
Berberine Phytosome
What a user said
“Berberine actually has a pretty substantial amount of research on it for lowering LDL cholesterol. While the phytosome version doesn't have specific studies for LDL lowering that I'm aware of, it made a massive difference on my bloodwork personally.”
Full Berberine Phytosome profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate