Berberine vs Berberine Phytosome for energy
Short answer: For energy, more users report improvement with Berberine — 95% of 19 reports, versus 50% of 4 for Berberine Phytosome.
Berberine has 109 meta-analyses and 110 randomized trials on PubMed; Berberine Phytosome has 0 and 0.
Based on 288 reports about Berberine and 20 about Berberine Phytosome. Not medical advice.
| Berberine Supplement | Berberine Phytosome Supplement | |
|---|---|---|
| User score | 47 | 29 |
| Verdict | Mixed | Mostly positive |
| Positive of reports that state an outcome | 58% | 75% |
| Reports | 288 | 20 |
| Research | AResearch: Strong | DResearch: None |
| Meta-analyses / RCTs | 109 / 110 | 0 / 0 |
| Mainly used for | ||
| Weight loss % reporting improvement | 84% (19) | — |
| Appetite % reporting improvement | 87% (15) | — |
| Focus % reporting improvement | 33% (6) | — |
| Energy % reporting improvement | 95% (19) | 50% (4) |
| Sleep % reporting improvement | 75% (4) | — |
| Anxiety % reporting improvement | 50% (8) | — |
| Mood % reporting improvement | 92% (12) | 50% (2) |
| Performance % reporting improvement | 67% (3) | — |
| Pain & inflammation % reporting improvement | 100% (4) | — |
| Digestion % reporting improvement | 57% (14) | — |
| Hormones % reporting improvement | 67% (3) | — |
| Blood sugar % reporting improvement | 86% (58) | 100% (2) |
| Heart & lipids % reporting improvement | 92% (13) | 100% (2) |
| Longevity % reporting improvement | 50% (2) | — |
| Common side effects | stomach issues, anxiety, fatigue, brain fog | fatigue, drowsiness, depression |
| Typical dose reported | 400-500 mg / daily | 1-2 doses / morning/2x daily |
BerberineFull Berberine profile →
Latest review conclusion
Treatment with berberine may be safe since it does not increase the incidence of total adverse events and the risk of hypoglycemia. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=292975, identifier CRD42021292975.
Front Pharmacol, 2022 ↗What a user said
“I also use Berberine to keep insulin low but it doesn't do a lot of the other stuff metformin does”
Berberine PhytosomeFull Berberine Phytosome profile →
What a user said
“For those wanting the blood sugar regulating effects of berberine, they can just take one dose in the morning and have it last a long longer without spikes/drops”
Related comparisons
Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate