ALA vs Semaglutide for blood sugar
Short answer: For blood sugar, more users report improvement with ALA — 100% of 9 reports, versus 90% of 10 for Semaglutide.
ALA has 100 meta-analyses and 243 randomized trials on PubMed; Semaglutide has 421 and 307.
Based on 320 reports about ALA and 330 about Semaglutide. Not medical advice.
| ALA Supplement | Semaglutide Medication | |
|---|---|---|
| Users say it helped | 65%helped54 reports · medium confidence | 64%helped228 reports · high confidence |
| Verdict | Mostly positive | Mostly positive |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 100 / 243 | 421 / 307 |
| Mainly used for | ||
| Weight loss % reporting improvement | 50% (2) | 85% (138) |
| Appetite % reporting improvement | 100% (3) | 80% (70) |
| Energy % reporting improvement | 100% (15) | 39% (23) |
| Blood sugar % reporting improvement | 100% (9) | 90% (10) |
| Mood % reporting improvement | 100% (4) | 27% (11) |
| Common side effects | liver damage, headache, fatty liver, mercury brain | nausea, fatigue, stomach issues, constipation |
| Typical dose reported | 600 mg / daily | Not listed |
ALA treatment had favorable effects on DSPN by reducing sensory symptoms, and it resulted in a dose-dependent response relative to the placebo for TSS and the global satisfaction score. The use of ALA to prevent neurological symptoms should be further researched.
Nutrients, 2023 ↗“I also take alcar, alpha lipoic acid, choline, and pqq, but... there is some difference with these, but not as major as with CoQ10.”
This study shows that new anti-diabetic drugs, particularly GLP1-RA and Tirzepatide, are the most effective in inducing weight loss in patients with type 2 diabetes. Interestingly, exenatide appears to be the only GLP1-RA that induces a mild weight loss.
Pharmacol Res, 2021 ↗“I've lost 35lbs since then and now I'm in the Healthy range on BMI. My IBSD has virtually disappeared.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate