PlainPill

What people actually say

10,564 first-hand quotes, shortened but never edited — each links to the original discussion.

AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
L-DopaMixed
“I took P5P, zinc, L-dipa, tyrosine and ext supplements you guys recommended”
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L-DopaMixed
“ive tried 98% l-dopa and hated it, crashed hard after 40 minutes to 1h”
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L-DopaMixed
“I would be particularly careful with both the Mucuna pruriens, L-DOPA, and Rhodiola”
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L-DopaMixed
“I don't think L-Dopa is going to help you at all.”
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L-DopaMixed
“I took some L-Dopa and triggered a nasty reaction”
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SarcosineMostly positive
“sarcosine + NAC nailed it. I literally cannot tell the difference. I feel so amazing.”
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SarcosineMostly positive
“long courses of Sarcosine (daily for a month+ at a time) helped tremendously and permanently, however when I tried it again more recently it triggered anxiety and overthinking.”
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SarcosineMostly positive
“GlyT1 Inhibitors: Sarcosine and (lesser extent) dimethylglycine cause glycine reuptake inhibition, proven quite effective for anxiety ... Helps me a lot.”
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SarcosineMostly positive
“2000mg sarcosine helps with the emotional blunting often seen in schizophrenia, and it aids cognitive performance through enhanced NMDA signaling. I have taken both for a few weeks and they have helped me tremendously.”
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SarcosineMostly positive
“500mg sarcosine mid day every other day and I'm getting so much better.”
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SarcosineMostly positive
“Sarcosine has been the only supplement that made significant changes when it came to depression and parts of my anxiety.”
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SarcosineMostly positive
“One thing I add to NAC dose (2g or so) is also 2g of Sarcosine (methyl-glycine). This was in a supplement called profrontal. Can add in alpha Lipoic acid as an enhancer. This helps me a ton with anhedonia!”
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SarcosineMostly positive
“just 1 dose of sarcosine had me feeling incredible. It felt as though I could breathe again. Anxiety lifted, mood was relaxed but NOT tired”
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SarcosineMostly positive
“Nothings worked except Sarcosine which has helped me very subtly.”
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SarcosineMostly positive
“I've had considerable result with this stack, though, a bit inconsistent.”
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SarcosineMostly positive
“Sarcosine has been phenomenal for my social anxiety lately.”
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SarcosineMostly positive
“I combine it with N-Acetyl-Cystine and helps me with mood and anhedonia. I'm not sure about it's effects on sleep quality.”
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SarcosineMostly positive
“I got those symptoms after taking shit tons of it for a while... I think sarcosine and glycine help me reverse it... I remember being super anhedonic... Now I'm back to feeling caffeine pretty much as normal again. Sarcosine and glycine seemed to give me that energy and emotion back.”
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SarcosineMostly positive
“Sarcosine, a schizophrenic supplement treatment, has successfully treated my Dissociative Identity Disorder and about a whopping 43-68% of my crippling DPDR/dissociation/brain fog; am taking 500mg twice a day.”
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SarcosineMostly positive
“I've only been on Sarcosine (1 gram three times a day) for almost a week now, but it seems to have completely obliterated my old, self-destructively negative thinking patterns”
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SarcosineMostly positive
“I've since made the switch to ND's lemon balm tablets/sarcosine as well as gingko, 5-htp... been positive”
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SsrisMixed
“don't forget the SSRIs, that have proven very valuable for many people, me included.”
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SsrisMixed
“Prozac at 21 stole most of my libido. Found myself getting into riskier situations to feel the rush of desire I used to have much more organically.”
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SsrisMixed
“SSRIs have worked for me with no side effects. I swear I'm not BigPharma lol.”
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SsrisMixed
“SSRI’s I took when I was a teen gave me suicidal and homicidal thoughts that stopped when I stopped the medication.”
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SsrisMixed
“No other medication has helped - SSRIs, off label sedating anti psychotics, you name it - besides I hated them.”
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SsrisMixed
“My anxiety and depression were basically nonexistent while on them and it was great... due to side effects (emotional blunting, fatigue, etc.)”
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SsrisMixed
“SSRIs (I've tried Zoloft, Viibryd and Lexapro) work primarily on serotonin had zero positive effect on me in anxiety or depression.”
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SsrisMixed
“I’ve tried SSRIS but had 10-15 side effects and they were horrible.”
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SsrisMixed
“tried a whole bunch of SSRIs... most of which helped my mood but did fuck all for the kind of 'you stupid fuck...' thought loops.”
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SsrisMixed
“SSRI didn't solve ocd I had, D3 + fish oil + Mg solved.”
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SsrisMixed
“I got sick of the side effects when I was in my late teens and stopped taking medication, and the withdrawal period was one of the worst experiences of my life.”
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SsrisMixed
“Most of them defaulted to SSRIs, which have much worse side effects for me.”
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SsrisMixed
“I used a handful of SSRIs in the past and this is much better and nearly side effect free imo.”
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SsrisMixed
“Not a single thing has helped and has just given me gnarly side effects.”
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SsrisMixed
“SSRIs were very effective at improving my executive function at first, but now they barely work, and Prozac is the only one that really works for me.”
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SsrisMixed
“I used Ssri s for a few months. it does work quite well for anxiety, but unfortunately the side effects turned me into an unmotivated zombie”
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“I've done a ostrine+s-4 cycle before and gained about 6 pounds of lean mass and lost fat.”
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“Strength has definitely increased, and I've started noticing a much drier, more defined look...the night blindness has been the worst part. After around 8PM, everything takes on this weird green tint, and in low light I'm basically blind.”
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“I have noticed amazing increase in vascularity as well as pumps. Night vision sides are not bad.”
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