PlainPill

Vitamin D vs Vitamin E for hormones

Short answer: For hormones, users rate them about the same: 91% report improvement with Vitamin D (75 reports) and 90% with Vitamin E (10 reports).

Vitamin D has 3,251 meta-analyses and 4,560 randomized trials on PubMed; Vitamin E has 680 and 1,761.

Based on 3,058 reports about Vitamin D and 212 about Vitamin E. Not medical advice.

Vitamin D
Supplement
Vitamin E
Supplement
Users say it helped67%helped1,101 reports · high confidence47%helped36 reports · medium confidence
Verdict
Mostly positive
Mixed
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs3,251 / 4,560680 / 1,761
Mainly used for
Mood
% reporting improvement
88% (393)—
Energy
% reporting improvement
87% (255)100% (3)
Sleep
% reporting improvement
52% (119)—
Immunity
% reporting improvement
98% (94)—
Anxiety
% reporting improvement
64% (90)100% (2)
Common side effectsinsomnia, anxiety, hypercalcemia, nauseacarcinogenic at, cancer risk, diarrhea, dizziness
Typical dose reported10,000-20,000 IU / daily400 mg
Vitamin D
Latest review conclusion

These results indicate that the prevalence of vitamin D deficiency was more elevated in obese subjects. The vitamin D deficiency was associated with obesity irrespective of age, latitude, cut-offs to define vitamin D deficiency and the Human Development Index of the study location.

Obes Rev, 2015 ↗
What a user said
“First thing I noticed was my mood & libido, I have more 'feeling/sensitivity' down there.”
Full Vitamin D profile →
Vitamin E
Latest review conclusion

This study suggests the potential ability of vitamin C and E in alleviating pain symptoms experienced by individuals with endometriosis.

PLoS One, 2024 ↗
What a user said
“Vitamin E is the most effective supplement I've taken for anxiety, depression, lethargy, and anhedonia...even more effective than the SSRI.”
Full Vitamin E profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate