Vitamin B6 side effects
Across 522 first-hand reports, people mentioned a side effect 45 times (about 9 per 100 reports). The most common: neuropathy, numbness, vivid dreams. User reports show what people notice — they can't tell you whether Vitamin B6 is safe for you.
Reported side effects
neuropathy11
numbness7
vivid dreams7
anxiety6
peripheral neuropathy6
nerve damage5
tingling2
elevated dopamine/norepinephrine1
What got worse for some people
In their own words
“daily supplementation of B6 completely changed my life in the early aughts...I definitely felt as though I had some deficits in executive function, picking up on social cues, etc.”
“I actually once took B6 before going to sleep and experienced extremely vivid and lucid dreams, but they weren't restful at all.”
“B6 toxicity is a thing for me - makes my feet burn and feel tender.”
“50mg of B6 per day seems unnecessarily high... starts to mess up my sleep because my dreams become insaaane.”
“Too much B6 gives me anxiety and heart palpitations. Same with magnesium glycinate. Feels horrific.”
Is Vitamin B6 safe? What the research covers
AResearch: Strong152 meta-analyses · 261 randomized trials on PubMed
None of the top reviews we found focus on safety. All research on Vitamin B6.