People mainly take Sildenafil for performance. Based on 26 first-hand reports and 233 meta-analyses & systematic reviews in the medical literature. Ranked #305 of 2,750 overall.
Of reports that state an outcome, 36% are positive.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: Advances in biotechnologies together with insights from preclinical models will pave the way for developing personalized treatment regimens for patients with infertility-causing endometrial disorders such as AS/IUA, EA/TE, and endometritis. https://osf.io/th8yf/.
PubMed 38796750 ↗Conclusion: Tadalafil shares a similar efficacy and safety with sildenafil and significantly improves patients' sexual confidence. Furthermore, patients and their partners prefer tadalafil to sildenafil. Hence, tadalafil may be a better choice for ED treatment.
PubMed 28741090 ↗Conclusion: MNO + OSID is the most effective PPHN treatment. If iNO is not available, OSID + milrinone is preferred.
PubMed 38363176 ↗Conclusion: Treatment for CTD-PAH had favorable effects on clinical and hemodynamic outcomes but not on survival and NT-proBNP levels. Different from the previous meta-analyses that focused on 6-MWD, time to clinical worsening, and CW as outcomes, this meta-analysis additionally reports the pooled analysis of change in FC, hemodynamic measurements (RAP, PVR, CI), and NT-proBNP, some of which have prognostic value for PAH.
PubMed 38378970 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
Verbatim quotes, shortened only — each links to the original discussion.
“You can get generic sildenafil for like 10 cents a pill on indiamart”
“almost feels like getting a good workout and the sense of physical well-being and vitality you get after recovering from exertion”
“The Viagra didn't help my legs, but after a shit night of sleep I felt better than normal the next day.”
“Viagra improves acquisition and retention of memory in mice”
“I know a lot of gym bros who will take viagra before a workout. They feel like it helps but not sure the science”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate