PlainPill

L-Citrulline vs Sildenafil for libido

Short answer: For libido, more users report improvement with L-Citrulline — 98% of 48 reports, versus 93% of 14 for Sildenafil.

L-Citrulline has 14 meta-analyses and 101 randomized trials on PubMed; Sildenafil has 233 and 699.

Based on 231 reports about L-Citrulline and 68 about Sildenafil. Not medical advice.

L-Citrulline
Supplement
Sildenafil
Medication
Users say it helped77%helped99 reports · medium confidence54%helped33 reports · medium confidence
Verdict
Mostly positive
Mixed
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs14 / 101233 / 699
Mainly used for
Libido
% reporting improvement
98% (48)93% (14)
Performance
% reporting improvement
98% (45)100% (9)
Heart & lipids
% reporting improvement
95% (22)—
Energy
% reporting improvement
100% (11)—
Common side effectscold sore, dizziness, headache, increased urinationheadache, nasal congestion, low estrogen, tolerance
Typical dose reported8 g / 3x/weekNot listed
L-Citrulline
Latest review conclusion

Foods rich in polyphenols and nitrate provide trivial benefits for endurance exercise performance, although these effects may be food dependent. Highly trained endurance athletes do not appear to benefit from consuming nitrate-rich foods but may benefit from polyphenol consumption. Further research into food sources, dosage and supplementation duration to optimise the ergogenic response to polyphenol consumption is warranted. Further studies should evaluate whether differential sex-based responses to nitrate and polyphenol consumption are attributable to physiological differences or sample siz

J Int Soc Sports Nutr, 2021 ↗
What a user said
“Something I found that makes my meds work way better is Citrulline 2g + Arginine 2g twice daily.”
Full L-Citrulline profile →
Sildenafil
Latest review conclusion

Advances in biotechnologies together with insights from preclinical models will pave the way for developing personalized treatment regimens for patients with infertility-causing endometrial disorders such as AS/IUA, EA/TE, and endometritis. https://osf.io/th8yf/.

Hum Reprod Update, 2024 ↗
What a user said
“my only solution was using viagra which works like a bomb. note to use a low dose of 25mg viagra at a time”
Full Sildenafil profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate