Sarcosine reviews: what real users say
We read 89 first-hand mentions of Sarcosine from health and supplement communities. 31 of them say clearly how it went — and 63% of those say it helped.
Where people say it works: mood (96% of 23), anxiety (70% of 10), focus (83% of 6).
Most common complaints: irritability, headache, frequent urination, mania, anger. All side effects →
Positive experiences
“sarcosine + NAC nailed it. I literally cannot tell the difference. I feel so amazing.”
“GlyT1 Inhibitors: Sarcosine and (lesser extent) dimethylglycine cause glycine reuptake inhibition, proven quite effective for anxiety ... Helps me a lot.”
“2000mg sarcosine helps with the emotional blunting often seen in schizophrenia, and it aids cognitive performance through enhanced NMDA signaling. I have taken both for a few weeks and they have helped me tremendously.”
“500mg sarcosine mid day every other day and I'm getting so much better.”
“Sarcosine has been the only supplement that made significant changes when it came to depression and parts of my anxiety.”
“One thing I add to NAC dose (2g or so) is also 2g of Sarcosine (methyl-glycine). This was in a supplement called profrontal. Can add in alpha Lipoic acid as an enhancer. This helps me a ton with anhedonia!”
Negative and mixed experiences
“long courses of Sarcosine (daily for a month+ at a time) helped tremendously and permanently, however when I tried it again more recently it triggered anxiety and overthinking.”
“just 1 dose of sarcosine had me feeling incredible. It felt as though I could breathe again. Anxiety lifted, mood was relaxed but NOT tired”
Quotes are verbatim and link to the original public discussion. Information only — not medical advice. How we collect reports