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Does Sarcosine help with anxiety?

Possibly — but there are few reports. 70% of 10 people who reported on Sarcosine for anxiety say it improved. 0% noticed no change and 30% say it got worse.

Anxiety: what users report
70%better10 reports · few reports
7 better0 no change3 worse

What people say about Sarcosine and anxiety

“long courses of Sarcosine (daily for a month+ at a time) helped tremendously and permanently, however when I tried it again more recently it triggered anxiety and overthinking.”
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“GlyT1 Inhibitors: Sarcosine and (lesser extent) dimethylglycine cause glycine reuptake inhibition, proven quite effective for anxiety ... Helps me a lot.”
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“Sarcosine has been the only supplement that made significant changes when it came to depression and parts of my anxiety.”
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“just 1 dose of sarcosine had me feeling incredible. It felt as though I could breathe again. Anxiety lifted, mood was relaxed but NOT tired”
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What the research says

AResearch: Strong20 meta-analyses · 27 trials on PubMed

None of the top reviews we found look specifically at anxiety. See all research on Sarcosine.

Side effects people mention

irritability 2headache 1frequent urination 1mania 1anger 1

What else is Sarcosine used for?

Based on few reports — treat as anecdotal. Information only — not medical advice. How we count

Does Sarcosine help with anxiety? 70% of 10 users say yes — PlainPill