PlainPill

Rhodiola

People mainly take Rhodiola for energy, anxiety, mood. Based on 182 first-hand reports and 18 meta-analyses & systematic reviews in the medical literature. Ranked #50 of 1,974 overall.

55
User score
Mixed
30% positive9% mixed13% negative48% unclear

Of reports that state an outcome, 58% are positive.

Clinical research
AStrong research base
18
meta-analyses
45
RCTs
846
papers

What Rhodiola does, according to users

Of the people who reported each effect, the share who said it got better.

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

Nutrients · 2021 · Meta-analysis / systematic review
Plant Adaptogens-History and Future Perspectives

Conclusion: The data from the meta-analysis showed that plant adaptogens could provide a number of benefits in the treatment of chronic fatigue, cognitive impairment, and immune protection. In the future, there is great potential to register medicinal products that contain plant adaptogens for therapeutic purposes.

PubMed 34445021 ↗
Front Nutr · 2025 · Meta-analysis / systematic review
The effect of Rhodiola rosea supplementation on endurance performance and related biomarkers: a systematic review and meta-analysis

Conclusion: In conclusion, RR supplementation is an effective ergogenic aid for enhancing endurance performance and improving physiological biomarkers related to oxidative stress, muscle damage, and metabolic efficiency, though heterogeneity across studies warrants cautious interpretation. https://www.crd.york.ac.uk/prospero/, PROSPERO CRD42024619014.

PubMed 41080184 ↗
BMC Complement Altern Med · 2012 · Meta-analysis / systematic review
Rhodiola rosea for physical and mental fatigue: a systematic review

Conclusion: Research regarding R. rosea efficacy is contradictory. While some evidence suggests that the herb may be helpful for enhancing physical performance and alleviating mental fatigue, methodological flaws limit accurate assessment of efficacy. A rigorously-designed well reported RCT that minimizes bias is needed to determine true efficacy of R. rosea for fatigue.

PubMed 22643043 ↗
Phytother Res · 2007 · Meta-analysis / systematic review
Herbal medicines in the treatment of psychiatric disorders: a systematic review

Conclusion: The review addresses current issues in herbal psychotherapy: herbal safety, future areas of application, the relationship of herbal medicine with pharmaceuticals and the potential prescriptive integration of phytomedicines with synthetic psychotropic medicines. Particular attention is given to clinical and safety issues with St John's wort and kava.

PubMed 17562566 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

eveningsas reported
1/daydaily
1000 mgmorning, cycled
morningas reported
500 mgas reported
250 mgdaily

Reported side effects

How often each side effect came up across all reports.

jitteriness ×5fatigue ×3anxiety ×3crash ×1exhaustion ×1part of ×1anger ×1serotonin syndrome ×1

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“Rhodiola”
Source discussion ↗
“I've also used (and liked) the herb rhodiola as a caffeine alternative in the evenings.”
Source discussion ↗
“next thing to add rhodiola (proportion 3:1) 1/day”
Source discussion ↗
“mixing many natural 100% organic herbs and plants into small pills to treat anxiety, focus the mind, alleviate minor depression. damiana, avena sativa, rhodiola, ginko biloba, green tea, yerba mate.”
Source discussion ↗
“consider versions with Bacopa and/or Rhodiola”
Source discussion ↗
Top discussions (5)

Other options for energy

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate