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Does Pregnenolone help with anxiety?

Often, yes. 77% of 30 people who reported on Pregnenolone for anxiety say it improved. 7% noticed no change and 17% say it got worse. That is below the typical result for anxiety (85% across 95 options).

Anxiety: what users report
77%better30 reports · medium confidence
23 better2 no change5 worse

Ranked #68 of 95 for anxiety.

What people say about Pregnenolone and anxiety

“I know pregnenalone helped me with that anxiety... 25mg a day is wonderful.”
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“I've been taking pregnenolone, dhea, and tongkhat ali and it helps keep my mind straight while living alone, working alone.”
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“I've never felt more comfortable in my own skin, more calm, or stable. Things just feel right. But: Definitely not a keeper for me. Either no effect or I get more jittery/anxious.”
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“I have been taking it for a few months. It *seems* to have helped with weight control and metabolism/energy.”
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What the research says

AResearch: Strong12 meta-analyses · 36 trials on PubMed
Eur J Endocrinol · 2023
Anorexia nervosa and adrenal hormones: a systematic review and meta-analysis

Conclusion: Women with anorexia nervosa have higher cortisol levels and lower DHEA-S and testosterone levels compared to women without anorexia nervosa. This finding is important to consider when evaluating low-weight women for disorders involving the adrenal axis, especially Cushing's syndrome.

Side effects people mention

hair loss 3demotivation 2jitteriness 2androgenic symptoms 1withdrawal 1

What else is Pregnenolone used for?

Information only — not medical advice. How we count

Does Pregnenolone help with anxiety? 77% of 30 users say yes — PlainPill