Conclusion: Ten phytomedicines were identified as having preclinical investigations showing interaction with the GABA system, in addition to human clinical trials: kava, valerian, pennywort, hops, chamomile, Ginkgo biloba, passionflower, ashwagandha, skullcap, and lemon balm. Collectively, the literature reveals preclinical and clinical evidence for various phytomedicines modulating GABA-pathways, with comparative anxiolytic effect to the current array of pharmaceuticals, along with good safety and tolerability profiles.
Does Skullcap help with anxiety?
Yes, for most people. 100% of 31 people who reported on Skullcap for anxiety say it improved. 0% noticed no change and 0% say it got worse. That is above the typical result for anxiety (85% across 95 options).
Anxiety: what users report
100%better31 reports · medium confidence
31 better0 no change0 worse
Ranked #4 of 95 for anxiety.
What people say about Skullcap and anxiety
“So far I've tried skullcap and kava... which help for the anxiety insomnia.”
“If your specific issue is *anxiety*, then I would strong suggest **Skullcap** (American). It works very well and can be taken on as needed basis. I use a tincture of herbal equivalent 800-1000mg.”
“One of best anti-cortisol and anxiety supps I have tried.”
“Thanks to skullcap lateriflora and chamomile I havent touched my diazepam 4mg in about three months.”
What the research says
BResearch: Moderate5 meta-analyses · 3 trials on PubMed
Phytother Res · 2018
GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidenceSide effects people mention
dysphoria 1drowsiness 1liver damage 1unusual next 1
What else is Skullcap used for?
Information only — not medical advice. How we count