PlainPill

Emodin

The short answer. There isn't much data on Emodin yet — 4 mentions, 2 with a clear outcome — so treat these numbers as anecdotal. There is a moderate body of research — 16 meta-analyses and 3 trials.

What users report
100%helped2 reports · few reports
2 helped0 mixed0 didn't help

From 4 mentions in total — the rest didn't say how it went and aren't counted.

Clinical research
BModerate research base
16
meta-analyses
3
RCTs
3,619
papers

What Emodin does, according to users

Of the people who reported each effect, the share who said it got better.

betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

BModerate research base

At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.

Nutrients · 2024 · Meta-analysis / systematic review
Potential Effects of Bioactive Compounds of Plant-Based Foods and Medicinal Plants in Chronic Kidney Disease and Dialysis: A Systematic Review

Conclusion: These results suggest that bioactive compounds of plant-based foods and medicinal plants have promising effects in terms of preventing or treating CKD progression and appear to improve inflammation and antioxidant capacity and support cardiovascular benefits and renoprotective effects; however, it is recommended that further studies be carried out.

PubMed 39770942 ↗
Photodiagnosis Photodyn Ther · 2024 · Meta-analysis / systematic review
The effects of antimicrobial photocatalytic nanoparticles on the flexural strength of orthodontic acrylic resins: A systematic review and meta-analysis

Conclusion: Our study supports the use of low concentrations of photocatalytic nanoparticles, such as ZnO (≤2 %), TiO2 (≤3 %), Emo (≤0.5 %), Cur (≤0.5 %), CurNis (≤5 %), and U. lactuca (≤1 %), in orthodontic acrylic resins without compromising FS.

PubMed 38401821 ↗
J Ethnopharmacol · 2015 · Meta-analysis / systematic review
Traditional usages, botany, phytochemistry, pharmacology and toxicology of Polygonum multiflorum Thunb.: a review

Conclusion: Therapeutic potential of Polygonum multiflorum has been demonstrated in the conditions like Alzheimer׳s disease, Parkinson׳s disease, hyperlipidaemia, inflammation and cancer, which is attributed to the presence of various stilbenes, quinones, flavonoids, phospholipids and other compounds in the drug. On the other hand, the adverse effects (hepatotoxicity, nephrotoxicity, and embryonic toxicity) of this plant were caused by the quinones, such as emodin and rhein. Thus more pharmacological and toxicological mechanisms on main active compounds are necessary to be explored, especially the combine

PubMed 25449462 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

500mgas reported

Reported side effects

How often each side effect came up across all reports.

emotional blunting ×1

What users say

First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.

Other options for hormones

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate