People mainly take D-Aspartic Acid for hormones, libido, performance. Based on 70 first-hand reports and 7 meta-analyses & systematic reviews in the medical literature. Ranked #671 of 2,750 overall.
Of reports that state an outcome, 27% are positive.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: Morbidity and mortality may be avoided with rapid, effective treatment of SE. Treatment application and escalation remains delayed especially in outpatient settings, potentially leading to suboptimal outcomes. Implementation techniques and quality improvement methodologies may provide avenues for improving outcomes in SE.
PubMed 29884518 ↗Conclusion: The exceptions were β-hydroxy β-methylbutyrate and betaine, which can be considered effective for male athletes. Eurycoma longifolia, a blend of Punica granatum fruit rind and Theobroma cacao seed extracts (Tesnor™) and purified Shilajit extract (PrimaVie™) can be considered possibly effective for men with late-onset hypogonadism; Eurycoma longifolia and Withania somnifera possibly effective for healthy men; and a non-hormonal aromatase inhibitor (Novadex XT™) possibly effective for male athletes.
PubMed 37697053 ↗Conclusion: Our results suggest that D-repeat of ASPN gene is mainly associated with male patients. The D13 polymorphism plays a protective role for OA in Caucasians male individuals while D14 plays a risk factor for KOA in male patients.
PubMed 30407347 ↗Conclusion: The present meta-analysis suggests that the ASPN D-repeat polymorphism is not associated with an increased KOA risk. However, future large studies with gene-gene and gene-environment interactions are needed to validate these findings.
PubMed 28889984 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
Verbatim quotes, shortened only — each links to the original discussion.
“I took those and a selection of other herbal test boosters - ocimum sanctum, d-aspartic acid, tongkat, maca, tribulus - and none of these seemed to do anything.”
“D aspartic acid - this was the best for me.”
“Look into the following "experimental" supplements that may help”
“I love it, but I feel dumb as a post unless I take noopept or some racetam.”
“Anything legal and OTC that purports to increase test is snake oil (besides D-Aspartic Acid [examine link]) but as far as muscle growth goes it's apparently not enough to stimulate it.”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate