Does Citicoline help with anxiety?
Possibly — but there are few reports. 36% of 11 people who reported on Citicoline for anxiety say it improved. 9% noticed no change and 55% say it got worse.
Anxiety: what users report
36%better11 reports · few reports
4 better1 no change6 worse
What people say about Citicoline and anxiety
“I believe this had led to excessive accumulation of acetylcholine (ACh) and subsequent symptoms (depression, low mood, anxiety, etc).”
“It gives me 'relaxed energy', which is free from both depression and anxiety.”
“I notice CDP-choline helps verbal fluency and social function, but doses of 1-1.2g cause overwhelming stressful feelings.”
“After only a few days of citicoline I felt normal again... Daily anxiety completely gone and when I do get triggered I return to baseline within an hour.”
What the research says
AResearch: Strong39 meta-analyses · 106 trials on PubMed
None of the top reviews we found look specifically at anxiety. See all research on Citicoline.
Side effects people mention
depression 13headache 6anxiety 6irritability 3suicidal ideation 2
What else is Citicoline used for?
Based on few reports — treat as anecdotal. Information only — not medical advice. How we count