Conclusion: This guideline should enable addressing suboptimal and deficient status of a bundle of MNs in at-risk diseases. In particular, it offers practical advice on MN provision and monitoring during nutritional support.
PubMed 35365361 ↗Biotin
People mainly take Biotin for skin & hair. Based on 35 first-hand reports and 30 meta-analyses & systematic reviews in the medical literature. Ranked #503 of 1,974 overall.
Of reports that state an outcome, 40% are positive.
What Biotin does, according to users
Of the people who reported each effect, the share who said it got better.
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: For atypical phenotypes, next generation genetic testing can aid diagnosis and guide treatment. Updated classification systems for EA are discussed which may assist diagnosis and management.
PubMed 37008993 ↗Conclusion: A moderate certainty of evidence suggests a potential benefit in favor of HDB administered for 12 to 15 months in terms of ITW25 in patients with PMS. However, an important trade-off of this benefit is the high certainty of evidence suggesting an increased incidence of laboratory test interference when HDB is taken.
PubMed 34332461 ↗Conclusion: There are a variety of controlled trials addressing the effects of dietary interventions for MS with substantial variation in active treatment, comparator, and outcomes of interest. PUFA administration may not differ when compared to alternatives with regards to relapse rate, disability worsening, or overall clinical status in people with MS, but evidence is uncertain. Similarly, at present, there is insufficient evidence to determine whether supplementation with antioxidants or other dietary interventions have any impact on MS-related outcomes.
PubMed 32428983 ↗Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“Biotin, collagen, zinc, selenium, niacin(b3). It may take 3 months until the effects are seen”
“I have an vit a c e supp I take and collagen. I’ll add the biotin.”
“Today I’m going to add Insolar Biotin CoQ10”
“Biotin 100mcg”
“I also take plenty of B5 and Biotin”
Other options for skin & hair
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate