Vitamin K vs Vitamin K2 for mood
Short answer: For mood, more users report improvement with Vitamin K — 100% of 3 reports, versus 93% of 14 for Vitamin K2.
Vitamin K has 1,080 meta-analyses and 714 randomized trials on PubMed; Vitamin K2 has 36 and 99.
Based on 154 reports about Vitamin K and 697 about Vitamin K2. Not medical advice.
| Vitamin K Supplement | Vitamin K2 Supplement | |
|---|---|---|
| Users say it helped | 77%helped20 reports · medium confidence | 72%helped125 reports · high confidence |
| Verdict | Not enough data | Mostly positive |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 1,080 / 714 | 36 / 99 |
| Mainly used for | ||
| Heart & lipids % reporting improvement | 67% (3) | 91% (23) |
| Mood % reporting improvement | 100% (3) | 93% (14) |
| Energy % reporting improvement | — | 100% (7) |
| Libido % reporting improvement | — | 80% (5) |
| Sleep % reporting improvement | — | 60% (5) |
| Common side effects | arrhythmia, blood clotting | heart palpitations, anxiety, palpitations, insomnia |
| Typical dose reported | 120 mg | 75 mcg |
The certainty in the evidence supporting the perioperative management of anticoagulants remains limited. No high-quality evidence exists to support the practice of heparin bridging during the interruption of VKA or DOAC therapy for an elective surgery or procedure, or for the practice of interrupting VKA therapy for minor procedures, including cardiac device implantation, or continuation of a DOAC vs short-term interruption of a DOAC in the perioperative period.
Chest, 2023 ↗“Doctors wanted to put me on anti-depressants...but vitamin D & K gave me the energy to get out of bed and make changes.”
The results of this meta-analysis seem to indicate that VK2 supplementation has a positive effect on the maintenance and improvement of BMD LS in postmenopausal women, and it can also reduce the fracture incidence, serum uc-OC levels and the ratio of uc-OC to cOC. In conclusion, VK2 can indirectly promote bone mineralization and increase bone strength.
Front Public Health, 2022 ↗“i believe k2, B vitamins, and amino acids L carnitine and glutamine made a difference in my skin.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate