Potassium vs Vitamin K2 for heart & lipids
Short answer: For heart & lipids, users rate them about the same: 92% report improvement with Potassium (12 reports) and 91% with Vitamin K2 (23 reports).
Potassium has 1,135 meta-analyses and 4,061 randomized trials on PubMed; Vitamin K2 has 36 and 99.
Based on 152 reports about Potassium and 697 about Vitamin K2. Not medical advice.
| Potassium Supplement | Vitamin K2 Supplement | |
|---|---|---|
| Users say it helped | 68%helped58 reports · medium confidence | 72%helped125 reports · high confidence |
| Verdict | Mostly positive | Mostly positive |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 1,135 / 4,061 | 36 / 99 |
| Mainly used for | ||
| Heart & lipids % reporting improvement | 92% (12) | 91% (23) |
| Energy % reporting improvement | 92% (13) | 100% (7) |
| Mood % reporting improvement | 100% (5) | 93% (14) |
| Anxiety % reporting improvement | 83% (6) | 75% (4) |
| Sleep % reporting improvement | 100% (2) | 60% (5) |
| Common side effects | hyperkalemia, stomach issues, heart palpitations, dizziness | heart palpitations, anxiety, palpitations, insomnia |
| Typical dose reported | 400 mg / daily | 75 mcg |
We found strong evidence that antidepressants differ markedly in their physiological effects, particularly for cardiometabolic parameters. Treatment guidelines should be updated to reflect differences in physiological risk, but choice of antidepressant should be made on an individual basis, considering clinical presentation and preferences of patients, carers, and clinicians.
Lancet, 2025 ↗“I saw a research on how to fight high level of cortisol by combining magnesium and potassium before bed. I added in glycine to the mix. After that I started to sleep 4 hours then 5 then 6.”
The results of this meta-analysis seem to indicate that VK2 supplementation has a positive effect on the maintenance and improvement of BMD LS in postmenopausal women, and it can also reduce the fracture incidence, serum uc-OC levels and the ratio of uc-OC to cOC. In conclusion, VK2 can indirectly promote bone mineralization and increase bone strength.
Front Public Health, 2022 ↗“i believe k2, B vitamins, and amino acids L carnitine and glutamine made a difference in my skin.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate