Tirzepatide vs Yohimbine for weight loss
Short answer: For weight loss, users rate them about the same: 94% report improvement with Tirzepatide (206 reports) and 97% with Yohimbine (35 reports).
Tirzepatide has 214 meta-analyses and 132 randomized trials on PubMed; Yohimbine has 26 and 152.
Based on 428 reports about Tirzepatide and 202 about Yohimbine. Not medical advice.
| Tirzepatide Medication | Yohimbine Supplement | |
|---|---|---|
| Users say it helped | 75%helped287 reports · high confidence | 43%helped93 reports · medium confidence |
| Verdict | Mostly positive | Mixed |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 214 / 132 | 26 / 152 |
| Mainly used for | ||
| Weight loss % reporting improvement | 94% (206) | 97% (35) |
| Appetite % reporting improvement | 84% (79) | 80% (5) |
| Energy % reporting improvement | 44% (32) | 91% (22) |
| Libido % reporting improvement | 33% (6) | 93% (29) |
| Mood % reporting improvement | 63% (27) | 83% (6) |
| Common side effects | nausea, fatigue, anhedonia, constipation | anxiety, jitteriness, sweating, nausea |
| Typical dose reported | Not listed | 5 mg / pre cardio |
This study shows that new anti-diabetic drugs, particularly GLP1-RA and Tirzepatide, are the most effective in inducing weight loss in patients with type 2 diabetes. Interestingly, exenatide appears to be the only GLP1-RA that induces a mild weight loss.
Pharmacol Res, 2021 ↗“Tirzepatide works so well! Do some research in the r/peptides subreddit and the r/tirzepatide subreddit. It's the most effective thing I've ever seen for appetite suppressant.”
Finally, the available data does not support yohimbine supplementation or the use of Resurgex Plus® to improve athletic performance in elite soccer players. Still, more well-designed research with elite soccer players is needed to improve support and advice regarding the use of dietary supplements for athletic performance enhancement.
J Int Soc Sports Nutr, 2023 ↗“what I take atm is caffeine, yohimbine, huperzine a, and taurine. Those items for me give me more than enough energy.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate