Phenibut vs Vitamin D for mood
Short answer: For mood, users rate them about the same: 90% report improvement with Phenibut (181 reports) and 88% with Vitamin D (393 reports).
Phenibut has 3 meta-analyses and 1 randomized trials on PubMed; Vitamin D has 3,251 and 4,560.
Based on 1,030 reports about Phenibut and 3,058 about Vitamin D. Not medical advice.
| Phenibut Substance | Vitamin D Supplement | |
|---|---|---|
| Users say it helped | 43%helped628 reports · high confidence | 67%helped1,101 reports · high confidence |
| Verdict | Mixed | Mostly positive |
| Research | BResearch: Moderate | AResearch: Strong |
| Meta-analyses / RCTs | 3 / 1 | 3,251 / 4,560 |
| Mainly used for | ||
| Mood % reporting improvement | 90% (181) | 88% (393) |
| Anxiety % reporting improvement | 89% (419) | 64% (90) |
| Energy % reporting improvement | 79% (38) | 87% (255) |
| Sleep % reporting improvement | 86% (90) | 52% (119) |
| Focus % reporting improvement | 72% (47) | 83% (60) |
| Common side effects | withdrawal, tolerance, addiction, dependence | insomnia, anxiety, hypercalcemia, nausea |
| Typical dose reported | 500 mg | 10,000-20,000 IU / daily |
Phenibut withdrawal appears to have a range of severity. It is important to recognize that patients undergoing phenibut abstinence may have progressive symptom worsening during early withdrawal. All published cases of abrupt phenibut abstinence were admitted inpatients for symptom management. Benzodiazepines or barbiturates with adjunctive baclofen appear to be the most commonly used drugs for moderate to severe withdrawal. Outpatient management via slow phenibut tapers with or without adjunctive gamma-aminobutyric acid agonist therapy may be successful. However, there is no standard treatment
Clin Toxicol (Phila), 2023 ↗“Phenibut every 3 days. Hands down most effective I've tried. Plus you wake up feeling amazing.”
These results indicate that the prevalence of vitamin D deficiency was more elevated in obese subjects. The vitamin D deficiency was associated with obesity irrespective of age, latitude, cut-offs to define vitamin D deficiency and the Human Development Index of the study location.
Obes Rev, 2015 ↗“First thing I noticed was my mood & libido, I have more 'feeling/sensitivity' down there.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate