Omega-3 vs Tyrosine for mood
Short answer: For mood, users rate them about the same: 82% report improvement with Omega-3 (201 reports) and 83% with Tyrosine (160 reports).
Omega-3 has 1,341 meta-analyses and 3,093 randomized trials on PubMed; Tyrosine has 2,190 and 1,766.
Based on 1,959 reports about Omega-3 and 1,154 about Tyrosine. Not medical advice.
| Omega-3 Supplement | Tyrosine Supplement | |
|---|---|---|
| User score | 47 | 47 |
| Verdict | Mostly positive | Mixed |
| Positive of reports that state an outcome | 66% | 56% |
| Reports | 1,959 | 1,154 |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 1,341 / 3,093 | 2,190 / 1,766 |
| Mainly used for | ||
| Weight loss % reporting improvement | 100% (2) | — |
| Focus % reporting improvement | 82% (129) | 82% (206) |
| Energy % reporting improvement | 74% (42) | 89% (152) |
| Sleep % reporting improvement | 79% (24) | 30% (10) |
| Anxiety % reporting improvement | 75% (69) | 60% (40) |
| Mood % reporting improvement | 82% (201) | 83% (160) |
| Memory % reporting improvement | 78% (50) | 78% (9) |
| Performance % reporting improvement | 88% (16) | 100% (8) |
| Recovery % reporting improvement | 90% (20) | — |
| Pain & inflammation % reporting improvement | 91% (82) | 50% (4) |
| Digestion % reporting improvement | 22% (9) | — |
| Libido % reporting improvement | 71% (14) | 75% (12) |
| Hormones % reporting improvement | 100% (2) | 100% (6) |
| Blood sugar % reporting improvement | 50% (2) | — |
| Heart & lipids % reporting improvement | 76% (58) | — |
| Skin & hair % reporting improvement | 89% (38) | 67% (6) |
| Immunity % reporting improvement | 60% (10) | 100% (2) |
| Longevity % reporting improvement | 86% (7) | — |
| Common side effects | brain fog, anxiety, depression, fatigue | anxiety, insomnia, jitteriness, headache |
| Typical dose reported | sparingly | 500 mg / daily |
For glycated hemoglobin, there was no significant effect in the meta-analysis. This systematic review with meta-analysis demonstrated that supplementation with omega-3 has protective effects on diabetes parameters.
Crit Rev Food Sci Nutr, 2022 ↗“I do supplement a lot of fish oil and vitamin A as retinyl palmitate though. It has really helped my depression, anxiety and ADHD and has enabled me to stop using more serious psychiatric drugs for those things.”
In patients with EGFR-mutated NSCLC, first and third generation EGFR tyrosine kinase inhibitors, as well as combination therapies with antiangiogenesis, were associated with increased risks of cardiovascular adverse events. Risks were significantly higher with third generation compared with first generation inhibitors.
BMJ, 2025 ↗“I stack taurine with tyrosine and creatine and that has helped my mood noticeably and also helps me feel stronger and more energetic.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate