PlainPill

Omega-3 vs Rhodiola for mood

Short answer: For mood, users rate them about the same: 82% report improvement with Omega-3 (201 reports) and 83% with Rhodiola (126 reports).

Omega-3 has 1,341 meta-analyses and 3,093 randomized trials on PubMed; Rhodiola has 18 and 45.

Based on 1,959 reports about Omega-3 and 853 about Rhodiola. Not medical advice.

Omega-3
Supplement
Rhodiola
Supplement
User score4752
Verdict
Mostly positive
Mostly positive
Positive
of reports that state an outcome
66%62%
Reports1,959853
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs1,341 / 3,09318 / 45
Mainly used for
Weight loss
% reporting improvement
100% (2)—
Focus
% reporting improvement
82% (129)85% (71)
Energy
% reporting improvement
74% (42)86% (199)
Sleep
% reporting improvement
79% (24)38% (13)
Anxiety
% reporting improvement
75% (69)74% (117)
Mood
% reporting improvement
82% (201)83% (126)
Memory
% reporting improvement
78% (50)75% (4)
Performance
% reporting improvement
88% (16)100% (21)
Recovery
% reporting improvement
90% (20)—
Pain & inflammation
% reporting improvement
91% (82)—
Digestion
% reporting improvement
22% (9)—
Libido
% reporting improvement
71% (14)80% (5)
Hormones
% reporting improvement
100% (2)100% (4)
Blood sugar
% reporting improvement
50% (2)—
Heart & lipids
% reporting improvement
76% (58)40% (5)
Skin & hair
% reporting improvement
89% (38)—
Immunity
% reporting improvement
60% (10)50% (2)
Longevity
% reporting improvement
86% (7)—
Common side effectsbrain fog, anxiety, depression, fatigueanxiety, fatigue, insomnia, jitteriness
Typical dose reportedsparinglyevenings
Omega-3
Latest review conclusion

For glycated hemoglobin, there was no significant effect in the meta-analysis. This systematic review with meta-analysis demonstrated that supplementation with omega-3 has protective effects on diabetes parameters.

Crit Rev Food Sci Nutr, 2022 ↗
What a user said
“I do supplement a lot of fish oil and vitamin A as retinyl palmitate though. It has really helped my depression, anxiety and ADHD and has enabled me to stop using more serious psychiatric drugs for those things.”
Full Omega-3 profile →
Rhodiola
Latest review conclusion

The data from the meta-analysis showed that plant adaptogens could provide a number of benefits in the treatment of chronic fatigue, cognitive impairment, and immune protection. In the future, there is great potential to register medicinal products that contain plant adaptogens for therapeutic purposes.

Nutrients, 2021 ↗
What a user said
“This one not only reduces my social anxiety but actually puts me in a good mood and makes me feel more social.”
Full Rhodiola profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate