Kratom vs THC for anxiety
Short answer: For anxiety, more users report improvement with Kratom — 91% of 108 reports, versus 33% of 96 for THC.
Kratom has 18 meta-analyses and 5 randomized trials on PubMed; THC has 249 and 488.
Based on 568 reports about Kratom and 434 about THC. Not medical advice.
| Kratom Substance | THC Substance | |
|---|---|---|
| Users say it helped | 46%helped335 reports · high confidence | 26%helped295 reports · high confidence |
| Verdict | Mixed | Mixed |
| Research | BResearch: Moderate | AResearch: Strong |
| Meta-analyses / RCTs | 18 / 5 | 249 / 488 |
| Mainly used for | ||
| Anxiety % reporting improvement | 91% (108) | 33% (96) |
| Mood % reporting improvement | 87% (142) | 64% (58) |
| Sleep % reporting improvement | 75% (12) | 59% (95) |
| Energy % reporting improvement | 84% (88) | 56% (16) |
| Focus % reporting improvement | 77% (44) | 38% (40) |
| Common side effects | withdrawal, dependence, addiction, tolerance | anxiety, brain fog, vivid dreams, paranoia |
| Typical dose reported | 4 g / 2x daily | 7 mg / once a week |
Based on our analysis, patients using <20 g of kratom/d could be initiated on opioid agonist therapy with 4/1 mg-8/2 mg buprenorphine-naloxone/d, while patients using kratom doses >40 g/d could be initiated with 12/3 mg-16/4 mg of buprenorphine-naloxone/day.
J Addict Med, 2021 ↗“Green or white Kratom powder. My productivity and overall mood have skyrocketed. I dose 4 grams once per day and it’s worked wonders.”
Cannabis use was also associated with increased relapse rates, more hospitalizations and pronounced positive symptoms in psychotic patients. We make recommendations about the type of research that is required to better characterize the relationship between cannabis use and the development and outcomes of psychosis.
Eur Arch Psychiatry Clin Neurosci, 2020 ↗“once a week I smoke a little weed before the gym (sativa Pre-roll sour diesel from medmen) and it actually made me feel normal.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate