PlainPill

L-Glutamine vs Magnesium for digestion

Short answer: For digestion, more users report improvement with L-Glutamine — 90% of 21 reports, versus 83% of 29 for Magnesium.

L-Glutamine has 19 meta-analyses and 117 randomized trials on PubMed; Magnesium has 82 and 210.

Based on 86 reports about L-Glutamine and 1,860 about Magnesium. Not medical advice.

L-Glutamine
Supplement
Magnesium
Supplement
User score3851
Verdict
Mostly positive
Mostly positive
Positive
of reports that state an outcome
63%74%
Reports861,860
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs19 / 11782 / 210
Mainly used for
Appetite
% reporting improvement
—100% (2)
Focus
% reporting improvement
100% (2)77% (39)
Energy
% reporting improvement
75% (4)76% (72)
Sleep
% reporting improvement
50% (2)87% (325)
Anxiety
% reporting improvement
60% (10)89% (219)
Mood
% reporting improvement
89% (9)80% (95)
Memory
% reporting improvement
—100% (7)
Performance
% reporting improvement
50% (2)87% (15)
Recovery
% reporting improvement
80% (5)96% (24)
Pain & inflammation
% reporting improvement
—91% (33)
Digestion
% reporting improvement
90% (21)83% (29)
Libido
% reporting improvement
100% (2)62% (13)
Hormones
% reporting improvement
—91% (22)
Blood sugar
% reporting improvement
—100% (3)
Heart & lipids
% reporting improvement
—95% (22)
Skin & hair
% reporting improvement
—100% (2)
Immunity
% reporting improvement
—86% (7)
Longevity
% reporting improvement
—100% (3)
Common side effectsanxiety, stomach issues, weird feeling, glutamate spikesdrowsiness, diarrhea, stomach issues, vivid dreams
Typical dose reported5 gdaily
L-Glutamine
Latest review conclusion

Dentoxol mouthwashes, Plantago major extract, thyme honey extract, zinc oxide paste, vitamin B complex combined with GeneTime, and the consumption of L-glutamine are effective in diminishing the severity of OM. Pain intensity was lower with doxepin mouthwashes and diphenhydramine-lidocaine-antacid mouthwashes.

Acta Odontol Latinoam, 2023 ↗
What a user said
“Ashwaghanda, Phosphatidylserine, L-Glutamine, Probiotics, CurcuBrain (Longvida) etc. most of them didn't provide any meaningful and noticeable benefits”
Full L-Glutamine profile →
Magnesium
Latest review conclusion

This review confirms that the quality of literature is substandard for physicians to make well-informed recommendations on usage of oral magnesium for older adults with insomnia. However, given that oral magnesium is very cheap and widely available, RCT evidence may support oral magnesium supplements (less than 1 g quantities given up to three times a day) for insomnia symptoms.

BMC Complement Med Ther, 2021 ↗
What a user said
“Then: -Theanine -GABA -Magnesium -Melatonin -Time in a Sauna -Blue Blocking Glasses -Reading before bed”
Full Magnesium profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate