PlainPill

L-Glutamine vs Probiotics for digestion

Short answer: For digestion, more users report improvement with L-Glutamine — 90% of 21 reports, versus 81% of 59 for Probiotics.

L-Glutamine has 19 meta-analyses and 117 randomized trials on PubMed; Probiotics has 2,293 and 2,235.

Based on 86 reports about L-Glutamine and 373 about Probiotics. Not medical advice.

L-Glutamine
Supplement
Probiotics
Supplement
User score3843
Verdict
Mostly positive
Mostly positive
Positive
of reports that state an outcome
63%61%
Reports86373
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs19 / 1172,293 / 2,235
Mainly used for
Appetite
% reporting improvement
—100% (2)
Focus
% reporting improvement
100% (2)70% (10)
Energy
% reporting improvement
75% (4)78% (9)
Sleep
% reporting improvement
50% (2)67% (6)
Anxiety
% reporting improvement
60% (10)88% (25)
Mood
% reporting improvement
89% (9)100% (45)
Performance
% reporting improvement
50% (2)—
Recovery
% reporting improvement
80% (5)—
Digestion
% reporting improvement
90% (21)81% (59)
Libido
% reporting improvement
100% (2)—
Skin & hair
% reporting improvement
—100% (5)
Immunity
% reporting improvement
—100% (2)
Common side effectsanxiety, stomach issues, weird feeling, glutamate spikesstomach issues, brain fog, diarrhea, withdrawal
Typical dose reported5 gdaily
L-Glutamine
Latest review conclusion

Dentoxol mouthwashes, Plantago major extract, thyme honey extract, zinc oxide paste, vitamin B complex combined with GeneTime, and the consumption of L-glutamine are effective in diminishing the severity of OM. Pain intensity was lower with doxepin mouthwashes and diphenhydramine-lidocaine-antacid mouthwashes.

Acta Odontol Latinoam, 2023 ↗
What a user said
“Ashwaghanda, Phosphatidylserine, L-Glutamine, Probiotics, CurcuBrain (Longvida) etc. most of them didn't provide any meaningful and noticeable benefits”
Full L-Glutamine profile →
Probiotics
Latest review conclusion

Some combinations of probiotics or strains may be beneficial in IBS. However, certainty in the evidence for efficacy by GRADE criteria was low to very low across almost all of our analyses.

Gastroenterology, 2023 ↗
What a user said
“I take red yeast rice, coq10, vitamin d, vitamin c, a probiotic and a multivitamin.”
Full Probiotics profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate