L-Citrulline vs Tadalafil for libido
Short answer: For libido, more users report improvement with L-Citrulline — 97% of 37 reports, versus 91% of 82 for Tadalafil.
L-Citrulline has 14 meta-analyses and 101 randomized trials on PubMed; Tadalafil has 120 and 347.
Based on 181 reports about L-Citrulline and 214 about Tadalafil. Not medical advice.
| L-Citrulline Supplement | Tadalafil Medication | |
|---|---|---|
| User score | 57 | 65 |
| Verdict | Mostly positive | Mostly positive |
| Positive of reports that state an outcome | 76% | 78% |
| Reports | 181 | 214 |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 14 / 101 | 120 / 347 |
| Mainly used for | ||
| Focus % reporting improvement | 67% (3) | 88% (8) |
| Energy % reporting improvement | 100% (7) | 100% (6) |
| Sleep % reporting improvement | — | 100% (4) |
| Anxiety % reporting improvement | 100% (2) | 75% (4) |
| Mood % reporting improvement | 100% (2) | 100% (9) |
| Performance % reporting improvement | 97% (30) | 97% (61) |
| Recovery % reporting improvement | 100% (3) | 100% (6) |
| Pain & inflammation % reporting improvement | 100% (2) | 100% (2) |
| Libido % reporting improvement | 97% (37) | 91% (82) |
| Hormones % reporting improvement | 50% (2) | 100% (3) |
| Blood sugar % reporting improvement | — | 100% (2) |
| Heart & lipids % reporting improvement | 94% (16) | 100% (17) |
| Longevity % reporting improvement | — | 100% (2) |
| Common side effects | dizziness, headache, eye bags, tooth damage | headache, stuffy nose, heartburn, lower back |
| Typical dose reported | 8 g / 3x/week | 2.5-5 mg / daily or 5-10 mg every other day |
Foods rich in polyphenols and nitrate provide trivial benefits for endurance exercise performance, although these effects may be food dependent. Highly trained endurance athletes do not appear to benefit from consuming nitrate-rich foods but may benefit from polyphenol consumption. Further research into food sources, dosage and supplementation duration to optimise the ergogenic response to polyphenol consumption is warranted. Further studies should evaluate whether differential sex-based responses to nitrate and polyphenol consumption are attributable to physiological differences or sample siz
J Int Soc Sports Nutr, 2021 ↗“Something I found that makes my meds work way better is Citrulline 2g + Arginine 2g twice daily.”
Tadalafil shares a similar efficacy and safety with sildenafil and significantly improves patients' sexual confidence. Furthermore, patients and their partners prefer tadalafil to sildenafil. Hence, tadalafil may be a better choice for ED treatment.
Int Urol Nephrol, 2017 ↗“After a week of 2.5 mg twice a day, this is my favourite drug ever. My brain fog has gone...My mood is so much better, similar to an SSRI but without the flat feeling.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate