PlainPill

Kanna vs Saffron for mood

Short answer: For mood, users rate them about the same: 94% report improvement with Kanna (84 reports) and 92% with Saffron (165 reports).

Kanna has 8 meta-analyses and 0 randomized trials on PubMed; Saffron has 88 and 119.

Based on 231 reports about Kanna and 421 about Saffron. Not medical advice.

Kanna
Supplement
Saffron
Supplement
Users say it helped77%helped102 reports · high confidence62%helped223 reports · high confidence
Verdict
Mostly positive
Mostly positive
ResearchBResearch: ModerateAResearch: Strong
Meta-analyses / RCTs8 / 088 / 119
Mainly used for
Mood
% reporting improvement
94% (84)92% (165)
Anxiety
% reporting improvement
88% (42)81% (84)
Focus
% reporting improvement
100% (6)79% (38)
Energy
% reporting improvement
92% (13)81% (21)
Libido
% reporting improvement
100% (8)74% (19)
Common side effectsdrowsiness, appetite suppression, brain fog, agitationheadache, appetite suppression, insomnia, vivid dreams
Typical dose reported300mg sublingual30 mg
Kanna
Latest review conclusion

Additional top genes influence stress, immune, fear and threat-related processes, previously hypothesized to underlie PTSD neurobiology. These findings strengthen our understanding of neurobiological systems relevant to PTSD pathophysiology, while also opening new areas for investigation.

Nat Genet, 2024 ↗
What a user said
“Kanna tablets. Dissolve under the tongue...I can't sing Kannas praises enough. It's the instant cure for my brain fog, lack of energy, and lack of motivation.”
Full Kanna profile →
Saffron
Latest review conclusion

Saffron demonstrates promise in improving ADHD symptoms, with an acceptable safety profile. Future well-designed multicentral studies are suggested.

J Atten Disord, 2024 ↗
What a user said
“I just sneak some into whatever soup we are having. I honestly think it has made a huge difference.”
Full Saffron profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate