PlainPill

GHK-Cu vs HGH for skin & hair

Short answer: For skin & hair, more users report improvement with HGH — 97% of 32 reports, versus 87% of 202 for GHK-Cu.

GHK-Cu has 0 meta-analyses and 1 randomized trials on PubMed; HGH has 14 and 146.

Based on 496 reports about GHK-Cu and 433 about HGH. Not medical advice.

GHK-Cu
Peptide
HGH
Peptide
Users say it helped62%helped223 reports · high confidence65%helped199 reports · high confidence
Verdict
Mostly positive
Mostly positive
ResearchCResearch: LimitedAResearch: Strong
Meta-analyses / RCTs0 / 114 / 146
Mainly used for
Skin & hair
% reporting improvement
87% (202)97% (32)
Recovery
% reporting improvement
96% (27)95% (80)
Performance
% reporting improvement
100% (6)81% (58)
Weight loss
% reporting improvement
88% (8)93% (44)
Pain & inflammation
% reporting improvement
90% (31)68% (19)
Common side effectsinjection site, redness, stinging, injection painwater retention, carpal tunnel, joint pain, stomach issues
Typical dose reportedNot listedNot listed
GHK-Cu
What a user said
“Love it. 44 F. Totally helped even out my skin tone (Irish red cheeks), reduced wrinkles on my forehead and neck, thickened my hair which had been thinning, and grew my eye lashes.”
Full GHK-Cu profile →
HGH
Latest review conclusion

Many critical gaps remain in our knowledge of the pathogenesis, prevention, and management of endometrial trauma and IUAs. PROSPERO (ID: CRD42023366218).

Hum Reprod Update, 2025 ↗
What a user said
“one of my original accounts is regarding HGH . Posted it a while back . Helped me a lot.”
Full HGH profile →

Related comparisons

Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate