PlainPill

Curcumin vs Curcumin with Piperine for pain & inflammation

Short answer: For pain & inflammation, more users report improvement with Curcumin — 91% of 104 reports, versus 75% of 8 for Curcumin with Piperine.

Curcumin has 538 meta-analyses and 553 randomized trials on PubMed; the other has not been graded.

Based on 544 reports about Curcumin and 21 about Curcumin with Piperine. Not medical advice.

Curcumin
Supplement
Curcumin with Piperine
Supplement
Users say it helped61%helped180 reports · high confidence74%helped12 reports · few reports
Verdict
Mostly positive
Mostly positive
ResearchAResearch: StrongNot graded
Meta-analyses / RCTs538 / 553—
Mainly used for
Pain & inflammation
% reporting improvement
91% (104)75% (8)
Mood
% reporting improvement
96% (45)—
Anxiety
% reporting improvement
93% (15)—
Memory
% reporting improvement
100% (12)—
Focus
% reporting improvement
78% (9)—
Common side effectsvivid dreams, headache, nausea, dht suppressiongallbladder irritation, increased intestinal
Typical dose reported1000 mg / daily1 g
Curcumin
Latest review conclusion

Curcumin and Curcuma longa Extract may improve symptoms and inflammation levels in people with arthritis. However, due to the low quality and small quantity of RCTs, the conclusions need to be interpreted carefully.

Front Immunol, 2022 ↗
What a user said
“I recently stopped taking Curcumin because of its affect on DHT and I was looking for an alternative measure to deal with inflammation as I feel it really helped with anxiety/depression.”
Full Curcumin profile →
Curcumin with Piperine
What a user said
“i think about 85 percent of of symptoms are gone...What really helped in my opinion is the curcumim. The curcumin with piperine is a powerful anti oxidant.”
Full Curcumin with Piperine profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate