Creatine vs Creatine Hcl for performance
Short answer: For performance, more users report improvement with Creatine — 98% of 542 reports, versus 60% of 5 for Creatine Hcl.
Creatine has 763 meta-analyses and 2,794 randomized trials on PubMed; Creatine Hcl has 763 and 2,794.
Based on 2,279 reports about Creatine and 31 about Creatine Hcl. Not medical advice.
| Creatine Supplement | Creatine Hcl Supplement | |
|---|---|---|
| Users say it helped | 72%helped1,048 reports · high confidence | 36%helped14 reports · few reports |
| Verdict | Mostly positive | Mixed |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 763 / 2,794 | 763 / 2,794 |
| Mainly used for | ||
| Performance % reporting improvement | 98% (542) | 60% (5) |
| Energy % reporting improvement | 97% (268) | 100% (2) |
| Focus % reporting improvement | 93% (249) | — |
| Mood % reporting improvement | 87% (125) | — |
| Recovery % reporting improvement | 98% (95) | — |
| Common side effects | stomach issues, hair loss, insomnia, water retention | sleep issues, nausea, acid reflux, undigested pill |
| Typical dose reported | 5 g / daily | 2 g / before bed, in addition to morning dose |
The results of the meta-analysis suggest that creatine supplementation did not significantly alter serum creatinine levels (standardized mean difference = 0.48, 95% confidence interval 0.24-0.73, P = .001, I2 = 22%), and did not alter plasma urea values (standardized mean difference = 1.10, 95% confidence interval 0.34-1.85, P = .004, I2 = 28%). The findings indicate that creatine supplementation does not induce renal damage in the studied amounts and durations.
J Ren Nutr, 2019 ↗“I actually feel a lot better. Mentally clearer and more balanced, like I have my brain back.”
The results of the meta-analysis suggest that creatine supplementation did not significantly alter serum creatinine levels (standardized mean difference = 0.48, 95% confidence interval 0.24-0.73, P = .001, I2 = 22%), and did not alter plasma urea values (standardized mean difference = 1.10, 95% confidence interval 0.34-1.85, P = .004, I2 = 28%). The findings indicate that creatine supplementation does not induce renal damage in the studied amounts and durations.
J Ren Nutr, 2019 ↗“taking 2g of creatine hcl (in addition to my morning workout dose) and I have slept insanely well”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate