Citrulline vs COQ10 for heart & lipids
Short answer: For heart & lipids, users rate them about the same: 100% report improvement with Citrulline (14 reports) and 100% with COQ10 (21 reports).
Citrulline has 51 meta-analyses and 258 randomized trials on PubMed; COQ10 has 176 and 405.
Based on 157 reports about Citrulline and 713 about COQ10. Not medical advice.
| Citrulline Supplement | COQ10 Supplement | |
|---|---|---|
| Users say it helped | 84%helped58 reports · medium confidence | 65%helped164 reports · high confidence |
| Verdict | Mostly positive | Mostly positive |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 51 / 258 | 176 / 405 |
| Mainly used for | ||
| Energy % reporting improvement | 75% (4) | 93% (97) |
| Performance % reporting improvement | 100% (31) | 100% (7) |
| Heart & lipids % reporting improvement | 100% (14) | 100% (21) |
| Libido % reporting improvement | 90% (20) | 100% (3) |
| Focus % reporting improvement | — | 68% (19) |
| Common side effects | erectile dysfunction, tooth erosion, tooth enamel, gerd | aggression, brain fog, skin rash, stomach issues |
| Typical dose reported | 1 g | 200 mg |
Supplementation of some but not all micronutrients may benefit cardiometabolic health. This study highlights the importance of micronutrient diversity and the balance of benefits and risks to promote and maintain cardiovascular health in diverse populations. (Antioxidant Supplementation in the Prevention and Treatment of Cardiovascular Diseases; CRD42022315165).
J Am Coll Cardiol, 2022 ↗“try all the standard vasodilators - citrulline and agmatine helped me a lot.”
These findings suggested that CoQ10 pretreatment is an effective intervention in improving IVF/ICSI outcomes for women with DOR. Still, this meta-analysis included relatively limited sample sizes with poor descriptions of their methodologies. Rigorously conducted trials are needed in the future.
Ann Med, 2024 ↗“I rely on 200mg of Qunol Co-enzyme Q10 to take with my 40mg of Crestor to prevent statin side effects. Works wonderfully.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate