PlainPill

Cissus vs Cissus Quadrangularis for pain & inflammation

Short answer: For pain & inflammation, more users report improvement with Cissus — 100% of 8 reports, versus 90% of 10 for Cissus Quadrangularis.

Cissus has 6 meta-analyses and 13 randomized trials on PubMed; Cissus Quadrangularis has 6 and 12.

Based on 24 reports about Cissus and 21 about Cissus Quadrangularis. Not medical advice.

Cissus
Supplement
Cissus Quadrangularis
Supplement
Users say it helped100%helped7 reports · few reports91%helped12 reports · few reports
Verdict
Mostly positive
Mostly positive
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs6 / 136 / 12
Mainly used for
Pain & inflammation
% reporting improvement
100% (8)90% (10)
Recovery
% reporting improvement
—100% (5)
Common side effectsgaggingNone reported
Typical dose reported4 capsules / daily4800 mg
Cissus
Latest review conclusion

However, high-quality studies remain needed. Copyright © 2017 John Wiley & Sons, Ltd.

Phytother Res, 2017 ↗
What a user said
“This works more for bone regeneration but also reduces joint inflammation and seems to be helping me.”
Full Cissus profile →
Cissus Quadrangularis
Latest review conclusion

In conclusion, compounds containing ephedra, CQ, ginseng, bitter melon, and zingiber were found to be effective in the management of obesity. Attention to these natural compounds would open a new approach for novel therapeutic and more effective agents.

World J Gastroenterol, 2009 ↗
What a user said
“I have almost the same injury also from 2007. Cissus seems to be the only thing that really helps.”
Full Cissus Quadrangularis profile →

Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate