Cissus Quadrangularis
People mainly take Cissus Quadrangularis for mood, digestion, performance. Based on 4 first-hand reports. Ranked #1060 of 1,974 overall.
14
User score
Mostly positive25% positive0% mixed0% negative75% unclear
Of reports that state an outcome, 100% are positive.
Clinical research
Research pending
What Cissus Quadrangularis does, according to users
Of the people who reported each effect, the share who said it got better.
betterno changeworse
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
Research data for Cissus Quadrangularis is being compiled.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
No doses stated in the reports so far.
Reported side effects
How often each side effect came up across all reports.
No side effects reported so far.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“Cissus Quadrangularis, MSM, Vitamin C, Vitamin D3/K2, Magnesium, Curcumin and Fish Oil.”
“Cissus quadrangularis for serotonin increase and appetite reduction”
“When I'm on Cissus I don't get injured during training, ever.”
“Magnesium, D3 + K2, Boron, Cissus Quadrangularis”
Top discussions (4)
- What are your "secret" lesser known herbs/compounds/extracts that you swear by and not many know about? ↗
- In my late 70s and I've been helping my son take care of his 1 year old. My shoulders aren't what it used to be and the pain is getting worst from carrying the baby overtime. Would NR (nicotinamide riboside - niagen) help due to its research claims of delaying aging? ↗
- Are there supplements that can help remineralize dentin and/or tooth enamel? ↗
- Do joint recovery supplements work? ↗
Other options for mood
Resistance Training
Lifestyle · 53 reports
100% report better mood
Mostly positive
Retatrutide
Peptide · 298 reports
69% report better mood
Mostly positiveBResearch: Moderate
Caffeine + L-Theanine
Supplement · 46 reports
100% report better mood
Mostly positive
Tirzepatide
Medication · 219 reports
76% report better mood
Mostly positiveAResearch: Strong
Creatine Monohydrate
Supplement · 139 reports
88% report better mood
Mostly positiveAResearch: Strong
Magnesium Malate
Supplement · 103 reports
100% report better mood
Mostly positiveDResearch: None
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate