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CBD vs CBD Isolate for anxiety

Short answer: For anxiety, more users report improvement with CBD Isolate — 100% of 7 reports, versus 88% of 185 for CBD.

CBD has 286 meta-analyses and 344 randomized trials on PubMed; CBD Isolate has 0 and 4.

Based on 482 reports about CBD and 15 about CBD Isolate. Not medical advice.

CBD
Supplement
CBD Isolate
Supplement
Users say it helped59%helped236 reports · high confidence80%helped10 reports · few reports
Verdict
Mixed
Mostly positive
ResearchAResearch: StrongCResearch: Limited
Meta-analyses / RCTs286 / 3440 / 4
Mainly used for
Anxiety
% reporting improvement
88% (185)100% (7)
Sleep
% reporting improvement
72% (76)—
Pain & inflammation
% reporting improvement
80% (35)—
Mood
% reporting improvement
85% (34)—
Focus
% reporting improvement
83% (12)—
Common side effectsbrain fog, headache, wakefulness, subdued feelingdrowsiness, increased sweating, body odour, difficulty falling
Typical dose reported30-60 mg; 54 mg / after dinner; before bed100 mg / daily
CBD
Latest review conclusion

In addition, this meta-analysis focuses on the efficacy of CBD in treating anxiety disorders such as generalized anxiety disorder (GAD), social anxiety disorder (SAD), and post-traumatic stress disorder (PTSD). However, caution should be exercised in interpreting our findings due to the limited size of the clinical sample, and additional trials ought to be carried out if deemed necessary.

Psychiatry Res, 2024 ↗
What a user said
“I take it for sleeping and anxiety and it works so well, even after five years. I haven't build up any tolerance.”
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CBD Isolate
What a user said
“CBD isolate works. I take about 100 MG daily for anxiety. Works better than my prescription does.”
Full CBD Isolate profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate