Apigenin vs Valerian Root for sleep
Short answer: For sleep, users rate them about the same: 81% report improvement with Apigenin (77 reports) and 82% with Valerian Root (109 reports).
Apigenin has 36 meta-analyses and 11 randomized trials on PubMed; Valerian Root has 2 and 8.
Based on 277 reports about Apigenin and 233 about Valerian Root. Not medical advice.
| Apigenin Supplement | Valerian Root Supplement | |
|---|---|---|
| Users say it helped | 59%helped94 reports · medium confidence | 57%helped119 reports · high confidence |
| Verdict | Mixed | Mixed |
| Research | AResearch: Strong | BResearch: Moderate |
| Meta-analyses / RCTs | 36 / 11 | 2 / 8 |
| Mainly used for | ||
| Sleep % reporting improvement | 81% (77) | 82% (109) |
| Anxiety % reporting improvement | 95% (41) | 86% (36) |
| Mood % reporting improvement | 80% (15) | 100% (2) |
| Hormones % reporting improvement | 100% (12) | — |
| Energy % reporting improvement | 57% (7) | — |
| Common side effects | vivid dreams, drowsiness, irritability, liver injury | vivid dreams, drowsiness, brain fog, tolerance |
| Typical dose reported | 50 mg | 500 mg / before bed |
The discovery of the beneficial effects of these natural active compounds in POL supports the idea that POL could be a promising novel candidate for the treatment and prevention of inflammation-related cancers of the digestive system. However, clinical data describing the mode of action of the naturally active compounds of POL are still lacking. In addition, pharmacokinetic data for POL compounds, such as changes in drug dose and absorption rates, cannot be extrapolated from animal models and need to be measured in patients in clinical trials. On the one hand, a systematic meta-analysis of the
J Ethnopharmacol, 2024 ↗“L theanine 200mg, apigenin 50mg, mag theo, mag biglycinate makes me pee too much, GABA 600mg, 3g taurine. I have anxiety and panic disorder late into nights. And this has cured about 80% for me.”
In conclusion, valerian could be a safe and effective herb to promote sleep and prevent associated disorders. However, due to the presence of multiple active constituents and relatively unstable nature of some of the active constituents, it may be necessary to revise the quality control processes, including standardization methods and shelf life.
J Evid Based Integr Med, 2020 ↗“I really like lemon balm especially if combined with valerian root! Helps me sleep and relax at night.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate