PlainPill

Apigenin vs Quercetin for energy

Short answer: For energy, more users report improvement with Quercetin — 100% of 8 reports, versus 57% of 7 for Apigenin.

Apigenin has 36 meta-analyses and 11 randomized trials on PubMed; Quercetin has 207 and 232.

Based on 277 reports about Apigenin and 280 about Quercetin. Not medical advice.

Apigenin
Supplement
Quercetin
Supplement
Users say it helped59%helped94 reports · medium confidence58%helped67 reports · medium confidence
Verdict
Mixed
Mixed
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs36 / 11207 / 232
Mainly used for
Sleep
% reporting improvement
81% (77)60% (5)
Anxiety
% reporting improvement
95% (41)25% (4)
Mood
% reporting improvement
80% (15)100% (2)
Pain & inflammation
% reporting improvement
—67% (15)
Energy
% reporting improvement
57% (7)100% (8)
Common side effectsvivid dreams, drowsiness, irritability, liver injuryinsomnia, jitteriness, anxiety, stimulation
Typical dose reported50 mg500-1000 mg
Apigenin
Latest review conclusion

The discovery of the beneficial effects of these natural active compounds in POL supports the idea that POL could be a promising novel candidate for the treatment and prevention of inflammation-related cancers of the digestive system. However, clinical data describing the mode of action of the naturally active compounds of POL are still lacking. In addition, pharmacokinetic data for POL compounds, such as changes in drug dose and absorption rates, cannot be extrapolated from animal models and need to be measured in patients in clinical trials. On the one hand, a systematic meta-analysis of the

J Ethnopharmacol, 2024 ↗
What a user said
“L theanine 200mg, apigenin 50mg, mag theo, mag biglycinate makes me pee too much, GABA 600mg, 3g taurine. I have anxiety and panic disorder late into nights. And this has cured about 80% for me.”
Full Apigenin profile →
Quercetin
Latest review conclusion

The results of a meta-analysis of 12 RCTs indicate that TCM intervention can improve the clinical treatment efficacy of CAG. NPAs identified seven hub TCM and 13 target genes associated with their actions, while bioinformatics analysis identified two DEGs between normal and CAG gastric tissues. Finally, molecular docking was employed to reveal the mechanism of action of the active molecules in TCM on the DEGs. These findings not only reveal the mechanisms of action of the active components of the TCMs, but also provide support for the development of new drugs, ultimately blocking the progressi

Ann Med, 2023 ↗
What a user said
“The above supplements have worked amazingly for my brain fog and motivation.”
Full Quercetin profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate